Human beige adipocytes for drug discovery and cell therapy in metabolic diseases

Methods to generate beige adipocytes from a human cell source are inefficient. Here, the authors present a protocol that efficiently generates beige adipocytes from human adipose-derived stem cells (ADSCs), which have potential utility in therapeutic development relating to metabolic diseases such a...

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Autores principales: Amar M. Singh, Liang Zhang, John Avery, Amelia Yin, Yuhong Du, Hui Wang, Zibo Li, Haian Fu, Hang Yin, Stephen Dalton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/dcf1a0bcf1ec452dab09549896e69ef7
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spelling oai:doaj.org-article:dcf1a0bcf1ec452dab09549896e69ef72021-12-02T17:51:11ZHuman beige adipocytes for drug discovery and cell therapy in metabolic diseases10.1038/s41467-020-16340-32041-1723https://doaj.org/article/dcf1a0bcf1ec452dab09549896e69ef72020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16340-3https://doaj.org/toc/2041-1723Methods to generate beige adipocytes from a human cell source are inefficient. Here, the authors present a protocol that efficiently generates beige adipocytes from human adipose-derived stem cells (ADSCs), which have potential utility in therapeutic development relating to metabolic diseases such as type 2 diabetes.Amar M. SinghLiang ZhangJohn AveryAmelia YinYuhong DuHui WangZibo LiHaian FuHang YinStephen DaltonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amar M. Singh
Liang Zhang
John Avery
Amelia Yin
Yuhong Du
Hui Wang
Zibo Li
Haian Fu
Hang Yin
Stephen Dalton
Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
description Methods to generate beige adipocytes from a human cell source are inefficient. Here, the authors present a protocol that efficiently generates beige adipocytes from human adipose-derived stem cells (ADSCs), which have potential utility in therapeutic development relating to metabolic diseases such as type 2 diabetes.
format article
author Amar M. Singh
Liang Zhang
John Avery
Amelia Yin
Yuhong Du
Hui Wang
Zibo Li
Haian Fu
Hang Yin
Stephen Dalton
author_facet Amar M. Singh
Liang Zhang
John Avery
Amelia Yin
Yuhong Du
Hui Wang
Zibo Li
Haian Fu
Hang Yin
Stephen Dalton
author_sort Amar M. Singh
title Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
title_short Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
title_full Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
title_fullStr Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
title_full_unstemmed Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
title_sort human beige adipocytes for drug discovery and cell therapy in metabolic diseases
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/dcf1a0bcf1ec452dab09549896e69ef7
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