CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes
Chromosome segregation is essential to avoid aneuploidy, yet in mammalian oocytes it progressively fails in an age-dependent manner. Here the authors identify CENP-V as a microtubule binding and bundling protein crucial to faithful oocyte meiosis, and present Cenp-V−/− oocytes as revealing age-depen...
Guardado en:
Autores principales: | Dalileh Nabi, Hauke Drechsler, Johannes Pschirer, Franz Korn, Nadine Schuler, Stefan Diez, Rolf Jessberger, Mariola Chacón |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/dcf979a98c334436b8bb21f92662b1b9 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Chromosome segregation occurs by microtubule pushing in oocytes
por: Kimberley Laband, et al.
Publicado: (2017) -
Actin-microtubule interplay coordinates spindle assembly in human oocytes
por: Johannes Roeles, et al.
Publicado: (2019) -
Active diffusion and advection in Drosophila oocytes result from the interplay of actin and microtubules
por: Maik Drechsler, et al.
Publicado: (2017) -
CENP-W plays a role in maintaining bipolar spindle structure.
por: Agnieszka Kaczmarczyk, et al.
Publicado: (2014) -
The mitotic spindle is chiral due to torques within microtubule bundles
por: Maja Novak, et al.
Publicado: (2018)