Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation

BACKGROUND AND OBJECTIVE: One of the most common complications after general anesthesia is nausea and vomiting that can cause spasm, hypoxia and pulmonary aspiration. Metoclopramide and dropridol are two common drugs to prevent nausea and vomiting after operation. On the other hand adding dexamethas...

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Autores principales: E Ali Jan Pour, Y Mortazavi, H Ale Reza
Formato: article
Lenguaje:EN
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Publicado: Babol University of Medical Sciences 2006
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Acceso en línea:https://doaj.org/article/dcfcc66c888b4d2fa873533e03ed09d1
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spelling oai:doaj.org-article:dcfcc66c888b4d2fa873533e03ed09d12021-11-10T09:12:49ZComparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation1561-41072251-7170https://doaj.org/article/dcfcc66c888b4d2fa873533e03ed09d12006-06-01T00:00:00Zhttp://jbums.org/article-1-2531-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: One of the most common complications after general anesthesia is nausea and vomiting that can cause spasm, hypoxia and pulmonary aspiration. Metoclopramide and dropridol are two common drugs to prevent nausea and vomiting after operation. On the other hand adding dexamethasone to these drugs is effective in decreasing nausea and vomiting. The purpose of this study was to compare the effect of metoclopramide and dropridol on prevention of nausea and vomiting after operation. METHODS: In this study, 160 patients were randomly divided into two groups of 80 patients. Patients in both groups were equally administered with premedication and induction of anesthesia according to their weight. The first group was injected with metoclopramide associated with dexamethasone and the second group was injected with dropridol associated with dexamethasone. After removing tracheal tube, nausea and vomiting in both groups were assessed for two hours and then data was compared to each other. FINDINGS: Postoperative nausea and vomiting in first group was 24% and in second one was 8%. Nausea and vomiting in females was more than males (p=0.049). CONCLUSION: According to the results, dropridol associated with dexamethasone can cause decreasing of nausea and vomiting in patients after general anesthesia.E Ali Jan PourY MortazaviH Ale RezaBabol University of Medical SciencesarticledropridolmetoclopramidedexamethasonenauseavomitingMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 8, Iss 3, Pp 32-35 (2006)
institution DOAJ
collection DOAJ
language EN
FA
topic dropridol
metoclopramide
dexamethasone
nausea
vomiting
Medicine
R
Medicine (General)
R5-920
spellingShingle dropridol
metoclopramide
dexamethasone
nausea
vomiting
Medicine
R
Medicine (General)
R5-920
E Ali Jan Pour
Y Mortazavi
H Ale Reza
Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation
description BACKGROUND AND OBJECTIVE: One of the most common complications after general anesthesia is nausea and vomiting that can cause spasm, hypoxia and pulmonary aspiration. Metoclopramide and dropridol are two common drugs to prevent nausea and vomiting after operation. On the other hand adding dexamethasone to these drugs is effective in decreasing nausea and vomiting. The purpose of this study was to compare the effect of metoclopramide and dropridol on prevention of nausea and vomiting after operation. METHODS: In this study, 160 patients were randomly divided into two groups of 80 patients. Patients in both groups were equally administered with premedication and induction of anesthesia according to their weight. The first group was injected with metoclopramide associated with dexamethasone and the second group was injected with dropridol associated with dexamethasone. After removing tracheal tube, nausea and vomiting in both groups were assessed for two hours and then data was compared to each other. FINDINGS: Postoperative nausea and vomiting in first group was 24% and in second one was 8%. Nausea and vomiting in females was more than males (p=0.049). CONCLUSION: According to the results, dropridol associated with dexamethasone can cause decreasing of nausea and vomiting in patients after general anesthesia.
format article
author E Ali Jan Pour
Y Mortazavi
H Ale Reza
author_facet E Ali Jan Pour
Y Mortazavi
H Ale Reza
author_sort E Ali Jan Pour
title Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation
title_short Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation
title_full Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation
title_fullStr Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation
title_full_unstemmed Comparison of the effect of Metoclopramide and Droperidol associated with Dexamethasone on nausea and vomiting after operation
title_sort comparison of the effect of metoclopramide and droperidol associated with dexamethasone on nausea and vomiting after operation
publisher Babol University of Medical Sciences
publishDate 2006
url https://doaj.org/article/dcfcc66c888b4d2fa873533e03ed09d1
work_keys_str_mv AT ealijanpour comparisonoftheeffectofmetoclopramideanddroperidolassociatedwithdexamethasoneonnauseaandvomitingafteroperation
AT ymortazavi comparisonoftheeffectofmetoclopramideanddroperidolassociatedwithdexamethasoneonnauseaandvomitingafteroperation
AT halereza comparisonoftheeffectofmetoclopramideanddroperidolassociatedwithdexamethasoneonnauseaandvomitingafteroperation
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