Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans
Duplications of gene segments can allow novel physiological adaptations to evolve. A detailed analysis of the TCAF gene family in primates and archaic humans suggest rapid duplication and diversification in this gene family is associated with cold or dietary adaptations.
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Nature Portfolio
2021
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oai:doaj.org-article:dd0c6ba953434ec38b1be1c12780fbb62021-12-02T19:02:36ZEvidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans10.1038/s41467-021-25435-42041-1723https://doaj.org/article/dd0c6ba953434ec38b1be1c12780fbb62021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25435-4https://doaj.org/toc/2041-1723Duplications of gene segments can allow novel physiological adaptations to evolve. A detailed analysis of the TCAF gene family in primates and archaic humans suggest rapid duplication and diversification in this gene family is associated with cold or dietary adaptations.PingHsun HsiehVy DangMitchell R. VollgerYafei MaoTzu-Hsueh HuangPhilip C. DishuckCarl BakerStuart CantsilierisAlexandra P. LewisKatherine M. MunsonMelanie SorensenAnneMarie E. WelchJason G. UnderwoodEvan E. EichlerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q |
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Science Q PingHsun Hsieh Vy Dang Mitchell R. Vollger Yafei Mao Tzu-Hsueh Huang Philip C. Dishuck Carl Baker Stuart Cantsilieris Alexandra P. Lewis Katherine M. Munson Melanie Sorensen AnneMarie E. Welch Jason G. Underwood Evan E. Eichler Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans |
description |
Duplications of gene segments can allow novel physiological adaptations to evolve. A detailed analysis of the TCAF gene family in primates and archaic humans suggest rapid duplication and diversification in this gene family is associated with cold or dietary adaptations. |
format |
article |
author |
PingHsun Hsieh Vy Dang Mitchell R. Vollger Yafei Mao Tzu-Hsueh Huang Philip C. Dishuck Carl Baker Stuart Cantsilieris Alexandra P. Lewis Katherine M. Munson Melanie Sorensen AnneMarie E. Welch Jason G. Underwood Evan E. Eichler |
author_facet |
PingHsun Hsieh Vy Dang Mitchell R. Vollger Yafei Mao Tzu-Hsueh Huang Philip C. Dishuck Carl Baker Stuart Cantsilieris Alexandra P. Lewis Katherine M. Munson Melanie Sorensen AnneMarie E. Welch Jason G. Underwood Evan E. Eichler |
author_sort |
PingHsun Hsieh |
title |
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans |
title_short |
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans |
title_full |
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans |
title_fullStr |
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans |
title_full_unstemmed |
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans |
title_sort |
evidence for opposing selective forces operating on human-specific duplicated tcaf genes in neanderthals and humans |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/dd0c6ba953434ec38b1be1c12780fbb6 |
work_keys_str_mv |
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