Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion

Cerebrovascular pathologies are commonly associated with dementia. Because air pollution increases arterial disease in humans and rodent models, we hypothesized that air pollution would also contribute to brain vascular dysfunction. We examined the effects of exposing mice to nanoparticulate matter...

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Bibliographic Details
Main Authors: Mikko T. Huuskonen, Qinghai Liu, Krista Lamorie-Foote, Kristina Shkirkova, Michelle Connor, Arati Patel, Axel Montagne, Hans Baertsch, Constantinos Sioutas, Todd E. Morgan, Caleb E. Finch, Berislav V. Zlokovic, William J. Mack
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
MRI
Online Access:https://doaj.org/article/dd0da04397864fab8976bf2c0b448859
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