Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome.

<h4>Study objective</h4>To explore the profile of patients who visit a sleep center with symptoms that fulfill the four essential criteria for restless legs syndrome (RLS).<h4>Design</h4>A prospective study.<h4>Setting</h4>Outpatients from one sleep disorders clin...

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Autores principales: Shih-Wei Lin, Yen-Lung Chen, Kuo-Chin Kao, Cheng-Ta Yang, Li-Pang Chuang, Yu-Ting Chou, Szu-Chia Lai, Rou-Shayn Chen, Ning-Hung Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/dd1c90dbc02747ceac66f0af3ad22ac0
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Sumario:<h4>Study objective</h4>To explore the profile of patients who visit a sleep center with symptoms that fulfill the four essential criteria for restless legs syndrome (RLS).<h4>Design</h4>A prospective study.<h4>Setting</h4>Outpatients from one sleep disorders clinic in Taiwan.<h4>Participants</h4>1,200 consecutive patients visit sleep disorders clinic with any sleep complaints.<h4>Interventions</h4>After completing a history and physical examination, all participants answered the RLS questionnaire. Subjects who fulfilled the four essential criteria for RLS were referred to a special clinic. A work-up including blood tests, polysomnography, and specialized neurological tests etc. was performed to make the final diagnosis.<h4>Measurements and results</h4>A total of 1,185 participants were enrolled, and, of these, 131(11.1%) fulfilled the four essential criteria for RLS, and 121 completed the supplemental work-up. Their mean age was 47.6±13.3 and 52.9% were male. Insomnia and snoring were the most common chief complaints. Obstructive sleep apnea syndrome and other diseases were found in 103 patients. Only 18 (14.9%) patients had no comorbid condition and were diagnosed with primary RLS.<h4>Conclusions</h4>Symptoms of RLS are common in patients with sleep complaints. Even in a sleep clinic, using a questionnaire approach for identification of RLS has a low positive predictive value. Clinicians should pay attention to the limitations of the 4-item questionnaire in diagnosis of RLS and also the importance of a careful differential diagnosis to identify possible secondary causes of RLS.