Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome.
<h4>Study objective</h4>To explore the profile of patients who visit a sleep center with symptoms that fulfill the four essential criteria for restless legs syndrome (RLS).<h4>Design</h4>A prospective study.<h4>Setting</h4>Outpatients from one sleep disorders clin...
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oai:doaj.org-article:dd1c90dbc02747ceac66f0af3ad22ac02021-11-18T08:59:09ZDiseases in patients coming to a sleep center with symptoms related to restless legs syndrome.1932-620310.1371/journal.pone.0071499https://doaj.org/article/dd1c90dbc02747ceac66f0af3ad22ac02013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23977057/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Study objective</h4>To explore the profile of patients who visit a sleep center with symptoms that fulfill the four essential criteria for restless legs syndrome (RLS).<h4>Design</h4>A prospective study.<h4>Setting</h4>Outpatients from one sleep disorders clinic in Taiwan.<h4>Participants</h4>1,200 consecutive patients visit sleep disorders clinic with any sleep complaints.<h4>Interventions</h4>After completing a history and physical examination, all participants answered the RLS questionnaire. Subjects who fulfilled the four essential criteria for RLS were referred to a special clinic. A work-up including blood tests, polysomnography, and specialized neurological tests etc. was performed to make the final diagnosis.<h4>Measurements and results</h4>A total of 1,185 participants were enrolled, and, of these, 131(11.1%) fulfilled the four essential criteria for RLS, and 121 completed the supplemental work-up. Their mean age was 47.6±13.3 and 52.9% were male. Insomnia and snoring were the most common chief complaints. Obstructive sleep apnea syndrome and other diseases were found in 103 patients. Only 18 (14.9%) patients had no comorbid condition and were diagnosed with primary RLS.<h4>Conclusions</h4>Symptoms of RLS are common in patients with sleep complaints. Even in a sleep clinic, using a questionnaire approach for identification of RLS has a low positive predictive value. Clinicians should pay attention to the limitations of the 4-item questionnaire in diagnosis of RLS and also the importance of a careful differential diagnosis to identify possible secondary causes of RLS.Shih-Wei LinYen-Lung ChenKuo-Chin KaoCheng-Ta YangLi-Pang ChuangYu-Ting ChouSzu-Chia LaiRou-Shayn ChenNing-Hung ChenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 8, p e71499 (2013) |
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Medicine R Science Q Shih-Wei Lin Yen-Lung Chen Kuo-Chin Kao Cheng-Ta Yang Li-Pang Chuang Yu-Ting Chou Szu-Chia Lai Rou-Shayn Chen Ning-Hung Chen Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
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<h4>Study objective</h4>To explore the profile of patients who visit a sleep center with symptoms that fulfill the four essential criteria for restless legs syndrome (RLS).<h4>Design</h4>A prospective study.<h4>Setting</h4>Outpatients from one sleep disorders clinic in Taiwan.<h4>Participants</h4>1,200 consecutive patients visit sleep disorders clinic with any sleep complaints.<h4>Interventions</h4>After completing a history and physical examination, all participants answered the RLS questionnaire. Subjects who fulfilled the four essential criteria for RLS were referred to a special clinic. A work-up including blood tests, polysomnography, and specialized neurological tests etc. was performed to make the final diagnosis.<h4>Measurements and results</h4>A total of 1,185 participants were enrolled, and, of these, 131(11.1%) fulfilled the four essential criteria for RLS, and 121 completed the supplemental work-up. Their mean age was 47.6±13.3 and 52.9% were male. Insomnia and snoring were the most common chief complaints. Obstructive sleep apnea syndrome and other diseases were found in 103 patients. Only 18 (14.9%) patients had no comorbid condition and were diagnosed with primary RLS.<h4>Conclusions</h4>Symptoms of RLS are common in patients with sleep complaints. Even in a sleep clinic, using a questionnaire approach for identification of RLS has a low positive predictive value. Clinicians should pay attention to the limitations of the 4-item questionnaire in diagnosis of RLS and also the importance of a careful differential diagnosis to identify possible secondary causes of RLS. |
format |
article |
author |
Shih-Wei Lin Yen-Lung Chen Kuo-Chin Kao Cheng-Ta Yang Li-Pang Chuang Yu-Ting Chou Szu-Chia Lai Rou-Shayn Chen Ning-Hung Chen |
author_facet |
Shih-Wei Lin Yen-Lung Chen Kuo-Chin Kao Cheng-Ta Yang Li-Pang Chuang Yu-Ting Chou Szu-Chia Lai Rou-Shayn Chen Ning-Hung Chen |
author_sort |
Shih-Wei Lin |
title |
Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
title_short |
Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
title_full |
Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
title_fullStr |
Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
title_full_unstemmed |
Diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
title_sort |
diseases in patients coming to a sleep center with symptoms related to restless legs syndrome. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2013 |
url |
https://doaj.org/article/dd1c90dbc02747ceac66f0af3ad22ac0 |
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