Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured.
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Nature Portfolio
2021
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oai:doaj.org-article:dd20a96647074b60be4f052131764d932021-12-02T16:51:13ZDirect contribution of skeletal muscle mesenchymal progenitors to bone repair10.1038/s41467-021-22842-52041-1723https://doaj.org/article/dd20a96647074b60be4f052131764d932021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22842-5https://doaj.org/toc/2041-1723Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured.Anais JulienAnuya KanagalingamEster Martínez-SarràJérome MegretMarine LukaMickaël MénagerFrédéric RelaixCéline ColnotNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Anais Julien Anuya Kanagalingam Ester Martínez-Sarrà Jérome Megret Marine Luka Mickaël Ménager Frédéric Relaix Céline Colnot Direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
description |
Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured. |
format |
article |
author |
Anais Julien Anuya Kanagalingam Ester Martínez-Sarrà Jérome Megret Marine Luka Mickaël Ménager Frédéric Relaix Céline Colnot |
author_facet |
Anais Julien Anuya Kanagalingam Ester Martínez-Sarrà Jérome Megret Marine Luka Mickaël Ménager Frédéric Relaix Céline Colnot |
author_sort |
Anais Julien |
title |
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
title_short |
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
title_full |
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
title_fullStr |
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
title_full_unstemmed |
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
title_sort |
direct contribution of skeletal muscle mesenchymal progenitors to bone repair |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/dd20a96647074b60be4f052131764d93 |
work_keys_str_mv |
AT anaisjulien directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT anuyakanagalingam directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT estermartinezsarra directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT jeromemegret directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT marineluka directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT mickaelmenager directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT fredericrelaix directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair AT celinecolnot directcontributionofskeletalmusclemesenchymalprogenitorstobonerepair |
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1718383009782038528 |