Direct contribution of skeletal muscle mesenchymal progenitors to bone repair

Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured.

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Autores principales: Anais Julien, Anuya Kanagalingam, Ester Martínez-Sarrà, Jérome Megret, Marine Luka, Mickaël Ménager, Frédéric Relaix, Céline Colnot
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dd20a96647074b60be4f052131764d93
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spelling oai:doaj.org-article:dd20a96647074b60be4f052131764d932021-12-02T16:51:13ZDirect contribution of skeletal muscle mesenchymal progenitors to bone repair10.1038/s41467-021-22842-52041-1723https://doaj.org/article/dd20a96647074b60be4f052131764d932021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22842-5https://doaj.org/toc/2041-1723Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured.Anais JulienAnuya KanagalingamEster Martínez-SarràJérome MegretMarine LukaMickaël MénagerFrédéric RelaixCéline ColnotNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anais Julien
Anuya Kanagalingam
Ester Martínez-Sarrà
Jérome Megret
Marine Luka
Mickaël Ménager
Frédéric Relaix
Céline Colnot
Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
description Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired when both muscle and bone are injured.
format article
author Anais Julien
Anuya Kanagalingam
Ester Martínez-Sarrà
Jérome Megret
Marine Luka
Mickaël Ménager
Frédéric Relaix
Céline Colnot
author_facet Anais Julien
Anuya Kanagalingam
Ester Martínez-Sarrà
Jérome Megret
Marine Luka
Mickaël Ménager
Frédéric Relaix
Céline Colnot
author_sort Anais Julien
title Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
title_short Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
title_full Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
title_fullStr Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
title_full_unstemmed Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
title_sort direct contribution of skeletal muscle mesenchymal progenitors to bone repair
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/dd20a96647074b60be4f052131764d93
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