The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions

Persistent infection with human papillomavirus can lead to cervical intraepithelial neoplasia (CIN). Here, the authors profile the vaginal microbiota in a cohort of non-pregnant young women diagnosed with CIN2 and find that absence of Lactobacillusspp. and presence of a diverse population of strict...

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Autores principales: Anita Mitra, David A. MacIntyre, George Ntritsos, Ann Smith, Konstantinos K. Tsilidis, Julian R. Marchesi, Phillip R. Bennett, Anna-Barbara Moscicki, Maria Kyrgiou
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/dd20c126438f416399fb56f1be0ed484
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spelling oai:doaj.org-article:dd20c126438f416399fb56f1be0ed4842021-12-02T14:41:26ZThe vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions10.1038/s41467-020-15856-y2041-1723https://doaj.org/article/dd20c126438f416399fb56f1be0ed4842020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15856-yhttps://doaj.org/toc/2041-1723Persistent infection with human papillomavirus can lead to cervical intraepithelial neoplasia (CIN). Here, the authors profile the vaginal microbiota in a cohort of non-pregnant young women diagnosed with CIN2 and find that absence of Lactobacillusspp. and presence of a diverse population of strict anaerobes associates with a decreased regression of untreated CIN2 lesions.Anita MitraDavid A. MacIntyreGeorge NtritsosAnn SmithKonstantinos K. TsilidisJulian R. MarchesiPhillip R. BennettAnna-Barbara MoscickiMaria KyrgiouNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anita Mitra
David A. MacIntyre
George Ntritsos
Ann Smith
Konstantinos K. Tsilidis
Julian R. Marchesi
Phillip R. Bennett
Anna-Barbara Moscicki
Maria Kyrgiou
The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
description Persistent infection with human papillomavirus can lead to cervical intraepithelial neoplasia (CIN). Here, the authors profile the vaginal microbiota in a cohort of non-pregnant young women diagnosed with CIN2 and find that absence of Lactobacillusspp. and presence of a diverse population of strict anaerobes associates with a decreased regression of untreated CIN2 lesions.
format article
author Anita Mitra
David A. MacIntyre
George Ntritsos
Ann Smith
Konstantinos K. Tsilidis
Julian R. Marchesi
Phillip R. Bennett
Anna-Barbara Moscicki
Maria Kyrgiou
author_facet Anita Mitra
David A. MacIntyre
George Ntritsos
Ann Smith
Konstantinos K. Tsilidis
Julian R. Marchesi
Phillip R. Bennett
Anna-Barbara Moscicki
Maria Kyrgiou
author_sort Anita Mitra
title The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
title_short The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
title_full The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
title_fullStr The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
title_full_unstemmed The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
title_sort vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/dd20c126438f416399fb56f1be0ed484
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