Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis

Ling Bei,1 Iris Lee,2 Michael S Lee,3 Greg P Van Stavern,1 Collin M McClelland3 1Department of Ophthalmology and Visual Neurosciences, Washington University School of Medicine, St Louis, MO, 2Casey Eye Institute, Oregon Health and Science University, Portland, OR, 3Department of Ophthalmology and Vi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bei L, Lee I, Lee MS, Van Stavern GP, McClell, CM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	giant cell arteritis fluorescein angiography delayed choroidal filling Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/dd21111778fa4afa885f50ccddacf8c5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:dd21111778fa4afa885f50ccddacf8c5
record_format	dspace
spelling	oai:doaj.org-article:dd21111778fa4afa885f50ccddacf8c52021-12-02T06:58:48ZAcute vision loss and choroidal filling delay in the absence of giant-cell arteritis1177-5483https://doaj.org/article/dd21111778fa4afa885f50ccddacf8c52016-09-01T00:00:00Zhttps://www.dovepress.com/acute-vision-loss-and-choroidal-filling-delay-in-the-absence-of-giant--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Ling Bei,1 Iris Lee,2 Michael S Lee,3 Greg P Van Stavern,1 Collin M McClelland3 1Department of Ophthalmology and Visual Neurosciences, Washington University School of Medicine, St Louis, MO, 2Casey Eye Institute, Oregon Health and Science University, Portland, OR, 3Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA Abstract: Giant-cell arteritis (GCA) is a visually devastating disease that often progresses to severe bilateral vision loss if untreated. Diagnosis of GCA is made challenging by the protean nature of the disease and the lack of a simple test that is both highly sensitive and specific. Choroidal filling delay on fluorescein angiography (FA) has been touted as a highly characteristic feature of GCA-related vision loss, although knowledge of both the sensitivity and specificity of this finding remains unproven. We report our experience of delayed choroidal filling on FA in a series of seven patients referred to an academic neuro-ophthalmology practice due to concern for GCA. Despite the FA findings, our examination, diagnostic testing, and long-term follow-up excluded the diagnosis of GCA in all cases, suggesting that choroidal perfusion abnormalities may occur in the absence of GCA. When evaluating a patient for acute vision loss, the astute clinician must remain cognizant of the limitations of FA in the diagnosis of GCA.Keywords: giant-cell arteritis, fluorescein angiography, delayed choroidal fillingBei LLee ILee MSVan Stavern GPMcClellCMDove Medical Pressarticlegiant cell arteritisfluorescein angiographydelayed choroidal fillingOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 1573-1578 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	giant cell arteritis fluorescein angiography delayed choroidal filling Ophthalmology RE1-994
spellingShingle	giant cell arteritis fluorescein angiography delayed choroidal filling Ophthalmology RE1-994 Bei L Lee I Lee MS Van Stavern GP McClell CM Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
description	Ling Bei,1 Iris Lee,2 Michael S Lee,3 Greg P Van Stavern,1 Collin M McClelland3 1Department of Ophthalmology and Visual Neurosciences, Washington University School of Medicine, St Louis, MO, 2Casey Eye Institute, Oregon Health and Science University, Portland, OR, 3Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA Abstract: Giant-cell arteritis (GCA) is a visually devastating disease that often progresses to severe bilateral vision loss if untreated. Diagnosis of GCA is made challenging by the protean nature of the disease and the lack of a simple test that is both highly sensitive and specific. Choroidal filling delay on fluorescein angiography (FA) has been touted as a highly characteristic feature of GCA-related vision loss, although knowledge of both the sensitivity and specificity of this finding remains unproven. We report our experience of delayed choroidal filling on FA in a series of seven patients referred to an academic neuro-ophthalmology practice due to concern for GCA. Despite the FA findings, our examination, diagnostic testing, and long-term follow-up excluded the diagnosis of GCA in all cases, suggesting that choroidal perfusion abnormalities may occur in the absence of GCA. When evaluating a patient for acute vision loss, the astute clinician must remain cognizant of the limitations of FA in the diagnosis of GCA.Keywords: giant-cell arteritis, fluorescein angiography, delayed choroidal filling
format	article
author	Bei L Lee I Lee MS Van Stavern GP McClell CM
author_facet	Bei L Lee I Lee MS Van Stavern GP McClell CM
author_sort	Bei L
title	Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
title_short	Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
title_full	Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
title_fullStr	Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
title_full_unstemmed	Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
title_sort	acute vision loss and choroidal filling delay in the absence of giant-cell arteritis
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/dd21111778fa4afa885f50ccddacf8c5
work_keys_str_mv	AT beil acutevisionlossandchoroidalfillingdelayintheabsenceofgiantcellarteritis AT leei acutevisionlossandchoroidalfillingdelayintheabsenceofgiantcellarteritis AT leems acutevisionlossandchoroidalfillingdelayintheabsenceofgiantcellarteritis AT vanstaverngp acutevisionlossandchoroidalfillingdelayintheabsenceofgiantcellarteritis AT mcclell acutevisionlossandchoroidalfillingdelayintheabsenceofgiantcellarteritis AT cm acutevisionlossandchoroidalfillingdelayintheabsenceofgiantcellarteritis
_version_	1718399666055282688

Acute vision loss and choroidal filling delay in the absence of giant-cell arteritis

Ejemplares similares