Fibroblast transition to an endothelial “trans” state improves cell reprogramming efficiency

Abstract Fibroblast reprogramming offers the potential for myocardial regeneration via in situ cell transdifferentiation. We explored a novel strategy leveraging endothelial cell plasticity to enhance reprogramming efficiency. Rat cardiac endothelial cells and fibroblasts were treated with Gata4, Me...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Megumi Mathison, Deepthi Sanagasetti, Vivek P. Singh, Aarthi Pugazenthi, Jaya Pratap Pinnamaneni, Christopher T. Ryan, Jianchang Yang, Todd K. Rosengart
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/dd218c69e5e94d91a0439e753722da4a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!