Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda

R Marshall Ford, Yousuf M KhalifaDavid and Ilene Flaum Eye Institute, University of Rochester Medical Center, Rochester, NY, USAAbstract: A 64-year-old Caucasian male complaining of redness and tearing for 3 years in both eyes was referred for evaluation of cicatricial conjunctivitis. Ocular cicatri...

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Autores principales:	Ford RM, Khalifa YM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/dd26e219f6264570824546110e8c691a
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spelling	oai:doaj.org-article:dd26e219f6264570824546110e8c691a2021-12-02T06:11:50ZImprovement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda1177-54671177-5483https://doaj.org/article/dd26e219f6264570824546110e8c691a2012-10-01T00:00:00Zhttp://www.dovepress.com/improvement-in-ocular-cicatricial-pemphigoid-following-treatment-for-p-a11341https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483R Marshall Ford, Yousuf M KhalifaDavid and Ilene Flaum Eye Institute, University of Rochester Medical Center, Rochester, NY, USAAbstract: A 64-year-old Caucasian male complaining of redness and tearing for 3 years in both eyes was referred for evaluation of cicatricial conjunctivitis. Ocular cicatricial pemphigoid was suspected and this diagnosis was confirmed through biopsy. The patient&#39;s condition showed moderate improvement following treatment with methotrexate and mycophenolate mofetil. The patient was later diagnosed with porphyria cutanea tarda and phlebotomy treatments were subsequently initiated. The patient&#39;s ocular symptoms improved further after he began receiving these phlebotomy treatments, and conventional treatment was discontinued. The authors hypothesize that circulating porphyrins activated by ultraviolet light could be the cause of the ocular cicatricial pemphigoid in this patient.Keywords: cicatricial conjunctivitis, phlebotomy treatments, circulating porphyrins, ultraviolet lightFord RMKhalifa YMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1709-1712 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Ford RM Khalifa YM Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
description	R Marshall Ford, Yousuf M KhalifaDavid and Ilene Flaum Eye Institute, University of Rochester Medical Center, Rochester, NY, USAAbstract: A 64-year-old Caucasian male complaining of redness and tearing for 3 years in both eyes was referred for evaluation of cicatricial conjunctivitis. Ocular cicatricial pemphigoid was suspected and this diagnosis was confirmed through biopsy. The patient&#39;s condition showed moderate improvement following treatment with methotrexate and mycophenolate mofetil. The patient was later diagnosed with porphyria cutanea tarda and phlebotomy treatments were subsequently initiated. The patient&#39;s ocular symptoms improved further after he began receiving these phlebotomy treatments, and conventional treatment was discontinued. The authors hypothesize that circulating porphyrins activated by ultraviolet light could be the cause of the ocular cicatricial pemphigoid in this patient.Keywords: cicatricial conjunctivitis, phlebotomy treatments, circulating porphyrins, ultraviolet light
format	article
author	Ford RM Khalifa YM
author_facet	Ford RM Khalifa YM
author_sort	Ford RM
title	Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
title_short	Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
title_full	Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
title_fullStr	Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
title_full_unstemmed	Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
title_sort	improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/dd26e219f6264570824546110e8c691a
work_keys_str_mv	AT fordrm improvementinocularcicatricialpemphigoidfollowingtreatmentforporphyriacutaneatarda AT khalifaym improvementinocularcicatricialpemphigoidfollowingtreatmentforporphyriacutaneatarda
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Improvement in ocular cicatricial pemphigoid following treatment for porphyria cutanea tarda

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