Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

Three-dimensional culture systems and organoids for mammary glands are important to understand mammary gland development. Here, the authors identify conditions (including Neuregulin 1 and R-spondin 1) that allow the culture of organoids that are responsive to hormonal stimulation for up to 2.5 month...

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Autores principales:	Thierry Jardé, Bethan Lloyd-Lewis, Mairian Thomas, Howard Kendrick, Lorenzo Melchor, Lauriane Bougaret, Peter D. Watson, Kenneth Ewan, Matthew J. Smalley, Trevor C. Dale
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dd27b68633a7410fb89e10d4f7836659
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spelling	oai:doaj.org-article:dd27b68633a7410fb89e10d4f78366592021-12-02T16:58:00ZWnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids10.1038/ncomms132072041-1723https://doaj.org/article/dd27b68633a7410fb89e10d4f78366592016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13207https://doaj.org/toc/2041-1723Three-dimensional culture systems and organoids for mammary glands are important to understand mammary gland development. Here, the authors identify conditions (including Neuregulin 1 and R-spondin 1) that allow the culture of organoids that are responsive to hormonal stimulation for up to 2.5 months.Thierry JardéBethan Lloyd-LewisMairian ThomasHoward KendrickLorenzo MelchorLauriane BougaretPeter D. WatsonKenneth EwanMatthew J. SmalleyTrevor C. DaleNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thierry Jardé Bethan Lloyd-Lewis Mairian Thomas Howard Kendrick Lorenzo Melchor Lauriane Bougaret Peter D. Watson Kenneth Ewan Matthew J. Smalley Trevor C. Dale Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
description	Three-dimensional culture systems and organoids for mammary glands are important to understand mammary gland development. Here, the authors identify conditions (including Neuregulin 1 and R-spondin 1) that allow the culture of organoids that are responsive to hormonal stimulation for up to 2.5 months.
format	article
author	Thierry Jardé Bethan Lloyd-Lewis Mairian Thomas Howard Kendrick Lorenzo Melchor Lauriane Bougaret Peter D. Watson Kenneth Ewan Matthew J. Smalley Trevor C. Dale
author_facet	Thierry Jardé Bethan Lloyd-Lewis Mairian Thomas Howard Kendrick Lorenzo Melchor Lauriane Bougaret Peter D. Watson Kenneth Ewan Matthew J. Smalley Trevor C. Dale
author_sort	Thierry Jardé
title	Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
title_short	Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
title_full	Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
title_fullStr	Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
title_full_unstemmed	Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
title_sort	wnt and neuregulin1/erbb signalling extends 3d culture of hormone responsive mammary organoids
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/dd27b68633a7410fb89e10d4f7836659
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Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

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