Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

Three-dimensional culture systems and organoids for mammary glands are important to understand mammary gland development. Here, the authors identify conditions (including Neuregulin 1 and R-spondin 1) that allow the culture of organoids that are responsive to hormonal stimulation for up to 2.5 month...

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Autores principales: Thierry Jardé, Bethan Lloyd-Lewis, Mairian Thomas, Howard Kendrick, Lorenzo Melchor, Lauriane Bougaret, Peter D. Watson, Kenneth Ewan, Matthew J. Smalley, Trevor C. Dale
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/dd27b68633a7410fb89e10d4f7836659
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