Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
Three-dimensional culture systems and organoids for mammary glands are important to understand mammary gland development. Here, the authors identify conditions (including Neuregulin 1 and R-spondin 1) that allow the culture of organoids that are responsive to hormonal stimulation for up to 2.5 month...
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Autores principales: | Thierry Jardé, Bethan Lloyd-Lewis, Mairian Thomas, Howard Kendrick, Lorenzo Melchor, Lauriane Bougaret, Peter D. Watson, Kenneth Ewan, Matthew J. Smalley, Trevor C. Dale |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/dd27b68633a7410fb89e10d4f7836659 |
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