Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs

The present study aimed to evaluate intramuscular xylazine HCl 2% as an anesthetic for laparogastrotomy in dogs at different doses. Twenty-seven dogs were divided randomly and equally into three groups; group A received 4 mg/kg, group B, received 8 mg/kg, and group C received 14 mg/kg. Anesthetic in...

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Autores principales:	Shereen Hussein, Ahmed Ibrahim, Enas Noseer, Mohamed Semieka
Formato:	article
Lenguaje:	EN
Publicado:	South Valley University 2020
Materias:	xylazine dogs anesthesia blood gases Agriculture S Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/dd3445aee0994526af0eb2957520af0e
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spelling	oai:doaj.org-article:dd3445aee0994526af0eb2957520af0e2021-12-02T12:07:13Z Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogsdoi:10.21608/SVU.2020.29353.10512535-18262535-1877https://doaj.org/article/dd3445aee0994526af0eb2957520af0e2020-05-01T00:00:00Zhttps://svu.journals.ekb.eg/article_91023.htmlhttps://doaj.org/toc/2535-1826https://doaj.org/toc/2535-1877The present study aimed to evaluate intramuscular xylazine HCl 2% as an anesthetic for laparogastrotomy in dogs at different doses. Twenty-seven dogs were divided randomly and equally into three groups; group A received 4 mg/kg, group B, received 8 mg/kg, and group C received 14 mg/kg. Anesthetic indices, effect on physiological parameters, blood gases, and biochemical parameters were recorded. The onset was 4.00 ± 0.00, 3.50 ± 0.33, and 5.00 ± 0.33 min, and the duration was 18.00 ± 2.50, 21.00 ± 7.20, and 28.00 ± 4.30 min in the groups A, B, and C, respectively. Pedal reflex was absent in groups A and B from 5 - 30 min post-injection. Palpebral reflex was absent in all groups from 20 - 30 min post-injection. All dogs recorded a non-significant decrease in the rectal temperature, but a significant decrease in respiratory and heart rates. There was a significant increase in the PvCO2 level and significant hyperglycemia in all dogs. Dogs in groups B and C exhibited a significant decrease in PvO2. There was a significant decrease in the serum cortisol level in the group B. Creatinine level recorded non-significant decrease in the group A, while there was a non-significant increase in the group B. There was non-significant decrease in GGT levels in the groups A and C. Xylazine at dose of 14 mg/kg established a satisfactory stable anesthesia that was enough to conduct laparogastrotomy in dogs. Shereen HusseinAhmed Ibrahim Enas NoseerMohamed SemiekaSouth Valley Universityarticlexylazinedogsanesthesiablood gasesAgricultureSVeterinary medicineSF600-1100ENSVU-International Journal of Veterinary Sciences, Vol 3, Iss 2, Pp 26-38 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	xylazine dogs anesthesia blood gases Agriculture S Veterinary medicine SF600-1100
spellingShingle	xylazine dogs anesthesia blood gases Agriculture S Veterinary medicine SF600-1100 Shereen Hussein Ahmed Ibrahim Enas Noseer Mohamed Semieka Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
description	The present study aimed to evaluate intramuscular xylazine HCl 2% as an anesthetic for laparogastrotomy in dogs at different doses. Twenty-seven dogs were divided randomly and equally into three groups; group A received 4 mg/kg, group B, received 8 mg/kg, and group C received 14 mg/kg. Anesthetic indices, effect on physiological parameters, blood gases, and biochemical parameters were recorded. The onset was 4.00 ± 0.00, 3.50 ± 0.33, and 5.00 ± 0.33 min, and the duration was 18.00 ± 2.50, 21.00 ± 7.20, and 28.00 ± 4.30 min in the groups A, B, and C, respectively. Pedal reflex was absent in groups A and B from 5 - 30 min post-injection. Palpebral reflex was absent in all groups from 20 - 30 min post-injection. All dogs recorded a non-significant decrease in the rectal temperature, but a significant decrease in respiratory and heart rates. There was a significant increase in the PvCO2 level and significant hyperglycemia in all dogs. Dogs in groups B and C exhibited a significant decrease in PvO2. There was a significant decrease in the serum cortisol level in the group B. Creatinine level recorded non-significant decrease in the group A, while there was a non-significant increase in the group B. There was non-significant decrease in GGT levels in the groups A and C. Xylazine at dose of 14 mg/kg established a satisfactory stable anesthesia that was enough to conduct laparogastrotomy in dogs.
format	article
author	Shereen Hussein Ahmed Ibrahim Enas Noseer Mohamed Semieka
author_facet	Shereen Hussein Ahmed Ibrahim Enas Noseer Mohamed Semieka
author_sort	Shereen Hussein
title	Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
title_short	Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
title_full	Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
title_fullStr	Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
title_full_unstemmed	Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs
title_sort	evaluation of xylazine hcl as a potential anesthetic for laprogastrotomy operation in dogs
publisher	South Valley University
publishDate	2020
url	https://doaj.org/article/dd3445aee0994526af0eb2957520af0e
work_keys_str_mv	AT shereenhussein evaluationofxylazinehclasapotentialanestheticforlaprogastrotomyoperationindogs AT ahmedibrahim evaluationofxylazinehclasapotentialanestheticforlaprogastrotomyoperationindogs AT enasnoseer evaluationofxylazinehclasapotentialanestheticforlaprogastrotomyoperationindogs AT mohamedsemieka evaluationofxylazinehclasapotentialanestheticforlaprogastrotomyoperationindogs
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Evaluation of Xylazine HCl as a Potential Anesthetic for Laprogastrotomy Operation in Dogs

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