Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for <named-content content-type="genus-species">Candida albicans</named-content> Cell Wall Maintenance

Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for <named-content content-type="genus-species">Candida albicans</named-content> Cell Wall Maintenance

ABSTRACT The Candida albicans high-affinity phosphate transporter Pho84 is required for normal Target of Rapamycin (TOR) signaling, oxidative stress resistance, and virulence of this fungal pathogen. It also contributes to C. albicans’ tolerance of two antifungal drug classes, polyenes and echinocan...

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Bibliographic Details
Main Authors: Ning-Ning Liu, Maikel Acosta-Zaldívar, Wanjun Qi, Joann Diray-Arce, Louise A. Walker, Theodore J. Kottom, Rachel Kelly, Min Yuan, John M. Asara, Jessica Ann Lasky-Su, Ofer Levy, Andrew H. Limper, Neil A. R. Gow, Julia R. Köhler
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
Candida albicans
Pho84
antifungal agents
cell wall
chitin synthase
glucan synthase
Microbiology
QR1-502
Online Access:https://doaj.org/article/dd3ae8e11a964f948c0d20db254e5bb3
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