Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis

Wen-Shin Lee, Edward E MancheDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, USAPurpose: The aim of the study was to determine and compare the relationship between change in simulated keratometry (K) and degree of refractive correction in wavefront-guided (WFG)...

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Autores principales:	Lee WS, Manche EE
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/dd3e979a0e1844df9ca60c4b6d6168cd
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spelling	oai:doaj.org-article:dd3e979a0e1844df9ca60c4b6d6168cd2021-12-02T07:51:33ZComparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis1177-5483https://doaj.org/article/dd3e979a0e1844df9ca60c4b6d6168cd2018-03-01T00:00:00Zhttps://www.dovepress.com/comparison-of-simulated-keratometric-changes-following-wavefront-guide-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Wen-Shin Lee, Edward E MancheDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, USAPurpose: The aim of the study was to determine and compare the relationship between change in simulated keratometry (K) and degree of refractive correction in wavefront-guided (WFG) and wavefront-optimized (WFO) myopic laser-assisted in situ keratomileusis (LASIK).Methods: A total of 51 patients were prospectively randomized to WFG LASIK in one eye and WFO LASIK in the contralateral eye at the Byers Eye Institute, Stanford University. Changes in simulated K and refractive error were determined at 1 year post-operatively. Linear regression was employed to calculate the slope of change in simulated K (ΔK) for change in refractive error (ΔSE). The mean ratio (ΔK/ΔSE) was also calculated.Results: The ratio of ΔK to ΔSE was larger for WFG LASIK compared to WFO LASIK when comparing the slope (ΔK/ΔSE) as determined by linear regression (0.85 vs 0.83, p = 0.04). Upon comparing the mean ratio (ΔK/ΔSE), subgroup analysis revealed that ΔK/ΔSE was larger for WFG LASIK for refractive corrections of >3.00 D and >4.00 D (0.89 vs 0.83; p = 0.0323 and 0.88 vs 0.83; p = 0.0466, respectively). Both linear regression and direct comparison of the mean ratio (ΔK/ΔSE) for refractive corrections <4.00 D and >4.00 D revealed no difference in ΔK/ΔSE between smaller and larger refractive corrections.Conclusion: WFO LASIK requires a smaller amount of corneal flattening compared to WFG LASIK for a given degree of refractive correction. For both, there was no significant difference in change in corneal curvature for a given degree of refractive error between smaller and larger corrections.Keywords: LASIK, keratometry, wavefront guided, wavefront optimized Lee WSManche EEDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 613-619 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Lee WS Manche EE Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
description	Wen-Shin Lee, Edward E MancheDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, USAPurpose: The aim of the study was to determine and compare the relationship between change in simulated keratometry (K) and degree of refractive correction in wavefront-guided (WFG) and wavefront-optimized (WFO) myopic laser-assisted in situ keratomileusis (LASIK).Methods: A total of 51 patients were prospectively randomized to WFG LASIK in one eye and WFO LASIK in the contralateral eye at the Byers Eye Institute, Stanford University. Changes in simulated K and refractive error were determined at 1 year post-operatively. Linear regression was employed to calculate the slope of change in simulated K (ΔK) for change in refractive error (ΔSE). The mean ratio (ΔK/ΔSE) was also calculated.Results: The ratio of ΔK to ΔSE was larger for WFG LASIK compared to WFO LASIK when comparing the slope (ΔK/ΔSE) as determined by linear regression (0.85 vs 0.83, p = 0.04). Upon comparing the mean ratio (ΔK/ΔSE), subgroup analysis revealed that ΔK/ΔSE was larger for WFG LASIK for refractive corrections of >3.00 D and >4.00 D (0.89 vs 0.83; p = 0.0323 and 0.88 vs 0.83; p = 0.0466, respectively). Both linear regression and direct comparison of the mean ratio (ΔK/ΔSE) for refractive corrections <4.00 D and >4.00 D revealed no difference in ΔK/ΔSE between smaller and larger refractive corrections.Conclusion: WFO LASIK requires a smaller amount of corneal flattening compared to WFG LASIK for a given degree of refractive correction. For both, there was no significant difference in change in corneal curvature for a given degree of refractive error between smaller and larger corrections.Keywords: LASIK, keratometry, wavefront guided, wavefront optimized
format	article
author	Lee WS Manche EE
author_facet	Lee WS Manche EE
author_sort	Lee WS
title	Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
title_short	Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
title_full	Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
title_fullStr	Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
title_full_unstemmed	Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
title_sort	comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/dd3e979a0e1844df9ca60c4b6d6168cd
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_version_	1718399189347467264

Comparison of simulated keratometric changes following wavefront-guided and wavefront-optimized myopic laser-assisted in situ keratomileusis

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