Does the use of acetylsalicylic acid have an influence on our vision?

Katarzyna Michalska-Małecka,1,2 Agnieszka Regucka,2 Dorota Śpiewak,2 Magdalena Sosnowska-Pońska,2 Alfred Niewiem2 1Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland; 2University Clinical Center, University Hospital Medical University of Sil...

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Autores principales:	Michalska-Małecka K, Regucka A, Śpiewak D, Sosnowska-Pońska M, Niewiem A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	acetylsalicylic acid AMD lipofuscin genesis drusen genesis retinal pigment epithelium cells geographic atrophy Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/dd411e9b727844f9b9bdb593e6eb77d9
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spelling	oai:doaj.org-article:dd411e9b727844f9b9bdb593e6eb77d92021-12-02T08:16:16ZDoes the use of acetylsalicylic acid have an influence on our vision?1178-1998https://doaj.org/article/dd411e9b727844f9b9bdb593e6eb77d92016-11-01T00:00:00Zhttps://www.dovepress.com/does-the-use-of-acetylsalicylic-acid-have-an-influence-on-our-vision-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Katarzyna Michalska-Małecka,1,2 Agnieszka Regucka,2 Dorota Śpiewak,2 Magdalena Sosnowska-Pońska,2 Alfred Niewiem2 1Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland; 2University Clinical Center, University Hospital Medical University of Silesia, Katowice, Poland Purpose: Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world due to its anti-inflammatory, analgesic, and antipyretic properties. This review aims to describe the relationship between acetylsalicylic acid and age-related macular degeneration (AMD) – a chronic disease that causes deterioration of visual acuity and is one of the most common ophthalmological diseases these days. Methods: Data presented in this review were collected from both research and review articles concerning ophthalmology and pharmacology. Results: The results of the studies analyzed in this review are not unambiguous. Moreover, the studies are not homogenous. They differed from one another in terms of the number of patients, the age criteria, the ASA dose, and the duration of control period. The reviewed studies revealed that ASA therapy, which is applied as a protection in cardiovascular diseases in patients with early forms of AMD and geographic atrophy, should not be discontinued. Conclusion: On the basis of the present studies, it cannot be unequivocally said whether ASA influences people’s vision and if people endangered with AMD progression or who are diagnosed with AMD should use this drug. It may increase the risk of AMD, but it can also reduce the risk of life-threatening conditions. The authors suggest that in order to avoid possible risks of AMD development, people who frequently take ASA should have their vision checked regularly. Keywords: acetylsalicylic acid, AMD, lipofuscin genesis, drusen genesis, retinal pigment epithelium cells, geographic atrophyMichalska-Małecka KRegucka AŚpiewak DSosnowska-Pońska MNiewiem ADove Medical Pressarticleacetylsalicylic acidAMDlipofuscin genesisdrusen genesisretinal pigment epithelium cellsgeographic atrophyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 1567-1574 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	acetylsalicylic acid AMD lipofuscin genesis drusen genesis retinal pigment epithelium cells geographic atrophy Geriatrics RC952-954.6
spellingShingle	acetylsalicylic acid AMD lipofuscin genesis drusen genesis retinal pigment epithelium cells geographic atrophy Geriatrics RC952-954.6 Michalska-Małecka K Regucka A Śpiewak D Sosnowska-Pońska M Niewiem A Does the use of acetylsalicylic acid have an influence on our vision?
description	Katarzyna Michalska-Małecka,1,2 Agnieszka Regucka,2 Dorota Śpiewak,2 Magdalena Sosnowska-Pońska,2 Alfred Niewiem2 1Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland; 2University Clinical Center, University Hospital Medical University of Silesia, Katowice, Poland Purpose: Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world due to its anti-inflammatory, analgesic, and antipyretic properties. This review aims to describe the relationship between acetylsalicylic acid and age-related macular degeneration (AMD) – a chronic disease that causes deterioration of visual acuity and is one of the most common ophthalmological diseases these days. Methods: Data presented in this review were collected from both research and review articles concerning ophthalmology and pharmacology. Results: The results of the studies analyzed in this review are not unambiguous. Moreover, the studies are not homogenous. They differed from one another in terms of the number of patients, the age criteria, the ASA dose, and the duration of control period. The reviewed studies revealed that ASA therapy, which is applied as a protection in cardiovascular diseases in patients with early forms of AMD and geographic atrophy, should not be discontinued. Conclusion: On the basis of the present studies, it cannot be unequivocally said whether ASA influences people’s vision and if people endangered with AMD progression or who are diagnosed with AMD should use this drug. It may increase the risk of AMD, but it can also reduce the risk of life-threatening conditions. The authors suggest that in order to avoid possible risks of AMD development, people who frequently take ASA should have their vision checked regularly. Keywords: acetylsalicylic acid, AMD, lipofuscin genesis, drusen genesis, retinal pigment epithelium cells, geographic atrophy
format	article
author	Michalska-Małecka K Regucka A Śpiewak D Sosnowska-Pońska M Niewiem A
author_facet	Michalska-Małecka K Regucka A Śpiewak D Sosnowska-Pońska M Niewiem A
author_sort	Michalska-Małecka K
title	Does the use of acetylsalicylic acid have an influence on our vision?
title_short	Does the use of acetylsalicylic acid have an influence on our vision?
title_full	Does the use of acetylsalicylic acid have an influence on our vision?
title_fullStr	Does the use of acetylsalicylic acid have an influence on our vision?
title_full_unstemmed	Does the use of acetylsalicylic acid have an influence on our vision?
title_sort	does the use of acetylsalicylic acid have an influence on our vision?
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/dd411e9b727844f9b9bdb593e6eb77d9
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Does the use of acetylsalicylic acid have an influence on our vision?

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