Assembly and functionality of the ribosome with tethered subunits
The tethered ribosome system Ribo-T supports cell proliferation though at a reduced rate. Here the authors show this is due to slower ribosome assembly instead of reduced functionality.
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Nature Portfolio
2019
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oai:doaj.org-article:dd41dd2510804c7598e1969fe536f5bc2021-12-02T17:01:54ZAssembly and functionality of the ribosome with tethered subunits10.1038/s41467-019-08892-w2041-1723https://doaj.org/article/dd41dd2510804c7598e1969fe536f5bc2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08892-whttps://doaj.org/toc/2041-1723The tethered ribosome system Ribo-T supports cell proliferation though at a reduced rate. Here the authors show this is due to slower ribosome assembly instead of reduced functionality.Nikolay A. AleksashinMargus LeppikAdam J. HockenberryDorota KlepackiNora Vázquez-LaslopMichael C. JewettJaanus RemmeAlexander S. MankinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Nikolay A. Aleksashin Margus Leppik Adam J. Hockenberry Dorota Klepacki Nora Vázquez-Laslop Michael C. Jewett Jaanus Remme Alexander S. Mankin Assembly and functionality of the ribosome with tethered subunits |
description |
The tethered ribosome system Ribo-T supports cell proliferation though at a reduced rate. Here the authors show this is due to slower ribosome assembly instead of reduced functionality. |
format |
article |
author |
Nikolay A. Aleksashin Margus Leppik Adam J. Hockenberry Dorota Klepacki Nora Vázquez-Laslop Michael C. Jewett Jaanus Remme Alexander S. Mankin |
author_facet |
Nikolay A. Aleksashin Margus Leppik Adam J. Hockenberry Dorota Klepacki Nora Vázquez-Laslop Michael C. Jewett Jaanus Remme Alexander S. Mankin |
author_sort |
Nikolay A. Aleksashin |
title |
Assembly and functionality of the ribosome with tethered subunits |
title_short |
Assembly and functionality of the ribosome with tethered subunits |
title_full |
Assembly and functionality of the ribosome with tethered subunits |
title_fullStr |
Assembly and functionality of the ribosome with tethered subunits |
title_full_unstemmed |
Assembly and functionality of the ribosome with tethered subunits |
title_sort |
assembly and functionality of the ribosome with tethered subunits |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/dd41dd2510804c7598e1969fe536f5bc |
work_keys_str_mv |
AT nikolayaaleksashin assemblyandfunctionalityoftheribosomewithtetheredsubunits AT margusleppik assemblyandfunctionalityoftheribosomewithtetheredsubunits AT adamjhockenberry assemblyandfunctionalityoftheribosomewithtetheredsubunits AT dorotaklepacki assemblyandfunctionalityoftheribosomewithtetheredsubunits AT noravazquezlaslop assemblyandfunctionalityoftheribosomewithtetheredsubunits AT michaelcjewett assemblyandfunctionalityoftheribosomewithtetheredsubunits AT jaanusremme assemblyandfunctionalityoftheribosomewithtetheredsubunits AT alexandersmankin assemblyandfunctionalityoftheribosomewithtetheredsubunits |
_version_ |
1718382054108823552 |