Optoacoustic brain stimulation at submillimeter spatial precision
Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves to activate neurons within a 500 μm radius in the...
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Nature Portfolio
2020
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oai:doaj.org-article:dd56232a95df4f95bdb7bdd299d544722021-12-02T17:32:12ZOptoacoustic brain stimulation at submillimeter spatial precision10.1038/s41467-020-14706-12041-1723https://doaj.org/article/dd56232a95df4f95bdb7bdd299d544722020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14706-1https://doaj.org/toc/2041-1723Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves to activate neurons within a 500 μm radius in the mouse brain.Ying JiangHyeon Jeong LeeLu LanHua-an TsengChen YangHeng-Ye ManXue HanJi-Xin ChengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Ying Jiang Hyeon Jeong Lee Lu Lan Hua-an Tseng Chen Yang Heng-Ye Man Xue Han Ji-Xin Cheng Optoacoustic brain stimulation at submillimeter spatial precision |
description |
Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves to activate neurons within a 500 μm radius in the mouse brain. |
format |
article |
author |
Ying Jiang Hyeon Jeong Lee Lu Lan Hua-an Tseng Chen Yang Heng-Ye Man Xue Han Ji-Xin Cheng |
author_facet |
Ying Jiang Hyeon Jeong Lee Lu Lan Hua-an Tseng Chen Yang Heng-Ye Man Xue Han Ji-Xin Cheng |
author_sort |
Ying Jiang |
title |
Optoacoustic brain stimulation at submillimeter spatial precision |
title_short |
Optoacoustic brain stimulation at submillimeter spatial precision |
title_full |
Optoacoustic brain stimulation at submillimeter spatial precision |
title_fullStr |
Optoacoustic brain stimulation at submillimeter spatial precision |
title_full_unstemmed |
Optoacoustic brain stimulation at submillimeter spatial precision |
title_sort |
optoacoustic brain stimulation at submillimeter spatial precision |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/dd56232a95df4f95bdb7bdd299d54472 |
work_keys_str_mv |
AT yingjiang optoacousticbrainstimulationatsubmillimeterspatialprecision AT hyeonjeonglee optoacousticbrainstimulationatsubmillimeterspatialprecision AT lulan optoacousticbrainstimulationatsubmillimeterspatialprecision AT huaantseng optoacousticbrainstimulationatsubmillimeterspatialprecision AT chenyang optoacousticbrainstimulationatsubmillimeterspatialprecision AT hengyeman optoacousticbrainstimulationatsubmillimeterspatialprecision AT xuehan optoacousticbrainstimulationatsubmillimeterspatialprecision AT jixincheng optoacousticbrainstimulationatsubmillimeterspatialprecision |
_version_ |
1718380401797365760 |