Optoacoustic brain stimulation at submillimeter spatial precision

Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves to activate neurons within a 500 μm radius in the...

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Autores principales: Ying Jiang, Hyeon Jeong Lee, Lu Lan, Hua-an Tseng, Chen Yang, Heng-Ye Man, Xue Han, Ji-Xin Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/dd56232a95df4f95bdb7bdd299d54472
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spelling oai:doaj.org-article:dd56232a95df4f95bdb7bdd299d544722021-12-02T17:32:12ZOptoacoustic brain stimulation at submillimeter spatial precision10.1038/s41467-020-14706-12041-1723https://doaj.org/article/dd56232a95df4f95bdb7bdd299d544722020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14706-1https://doaj.org/toc/2041-1723Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves to activate neurons within a 500 μm radius in the mouse brain.Ying JiangHyeon Jeong LeeLu LanHua-an TsengChen YangHeng-Ye ManXue HanJi-Xin ChengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ying Jiang
Hyeon Jeong Lee
Lu Lan
Hua-an Tseng
Chen Yang
Heng-Ye Man
Xue Han
Ji-Xin Cheng
Optoacoustic brain stimulation at submillimeter spatial precision
description Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves to activate neurons within a 500 μm radius in the mouse brain.
format article
author Ying Jiang
Hyeon Jeong Lee
Lu Lan
Hua-an Tseng
Chen Yang
Heng-Ye Man
Xue Han
Ji-Xin Cheng
author_facet Ying Jiang
Hyeon Jeong Lee
Lu Lan
Hua-an Tseng
Chen Yang
Heng-Ye Man
Xue Han
Ji-Xin Cheng
author_sort Ying Jiang
title Optoacoustic brain stimulation at submillimeter spatial precision
title_short Optoacoustic brain stimulation at submillimeter spatial precision
title_full Optoacoustic brain stimulation at submillimeter spatial precision
title_fullStr Optoacoustic brain stimulation at submillimeter spatial precision
title_full_unstemmed Optoacoustic brain stimulation at submillimeter spatial precision
title_sort optoacoustic brain stimulation at submillimeter spatial precision
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/dd56232a95df4f95bdb7bdd299d54472
work_keys_str_mv AT yingjiang optoacousticbrainstimulationatsubmillimeterspatialprecision
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AT lulan optoacousticbrainstimulationatsubmillimeterspatialprecision
AT huaantseng optoacousticbrainstimulationatsubmillimeterspatialprecision
AT chenyang optoacousticbrainstimulationatsubmillimeterspatialprecision
AT hengyeman optoacousticbrainstimulationatsubmillimeterspatialprecision
AT xuehan optoacousticbrainstimulationatsubmillimeterspatialprecision
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