A self-contained and self-explanatory DNA storage system

Abstract Current research on DNA storage usually focuses on the improvement of storage density by developing effective encoding and decoding schemes while lacking the consideration on the uncertainty in ultra-long-term data storage and retention. Consequently, the current DNA storage systems are oft...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Min Li, Jiashu Wu, Junbiao Dai, Qingshan Jiang, Qiang Qu, Xiaoluo Huang, Yang Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/dd599b22476a4bb98bbe91e9276329a7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:dd599b22476a4bb98bbe91e9276329a7
record_format	dspace
spelling	oai:doaj.org-article:dd599b22476a4bb98bbe91e9276329a72021-12-02T17:19:15ZA self-contained and self-explanatory DNA storage system10.1038/s41598-021-97570-32045-2322https://doaj.org/article/dd599b22476a4bb98bbe91e9276329a72021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97570-3https://doaj.org/toc/2045-2322Abstract Current research on DNA storage usually focuses on the improvement of storage density by developing effective encoding and decoding schemes while lacking the consideration on the uncertainty in ultra-long-term data storage and retention. Consequently, the current DNA storage systems are often not self-contained, implying that they have to resort to external tools for the restoration of the stored DNA data. This may result in high risks in data loss since the required tools might not be available due to the high uncertainty in far future. To address this issue, we propose in this paper a self-contained DNA storage system that can bring self-explanatory to its stored data without relying on any external tool. To this end, we design a specific DNA file format whereby a separate storage scheme is developed to reduce the data redundancy while an effective indexing is designed for random read operations to the stored data file. We verified through experimental data that the proposed self-contained and self-explanatory method can not only get rid of the reliance on external tools for data restoration but also minimise the data redundancy brought about when the amount of data to be stored reaches a certain scale.Min LiJiashu WuJunbiao DaiQingshan JiangQiang QuXiaoluo HuangYang WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Min Li Jiashu Wu Junbiao Dai Qingshan Jiang Qiang Qu Xiaoluo Huang Yang Wang A self-contained and self-explanatory DNA storage system
description	Abstract Current research on DNA storage usually focuses on the improvement of storage density by developing effective encoding and decoding schemes while lacking the consideration on the uncertainty in ultra-long-term data storage and retention. Consequently, the current DNA storage systems are often not self-contained, implying that they have to resort to external tools for the restoration of the stored DNA data. This may result in high risks in data loss since the required tools might not be available due to the high uncertainty in far future. To address this issue, we propose in this paper a self-contained DNA storage system that can bring self-explanatory to its stored data without relying on any external tool. To this end, we design a specific DNA file format whereby a separate storage scheme is developed to reduce the data redundancy while an effective indexing is designed for random read operations to the stored data file. We verified through experimental data that the proposed self-contained and self-explanatory method can not only get rid of the reliance on external tools for data restoration but also minimise the data redundancy brought about when the amount of data to be stored reaches a certain scale.
format	article
author	Min Li Jiashu Wu Junbiao Dai Qingshan Jiang Qiang Qu Xiaoluo Huang Yang Wang
author_facet	Min Li Jiashu Wu Junbiao Dai Qingshan Jiang Qiang Qu Xiaoluo Huang Yang Wang
author_sort	Min Li
title	A self-contained and self-explanatory DNA storage system
title_short	A self-contained and self-explanatory DNA storage system
title_full	A self-contained and self-explanatory DNA storage system
title_fullStr	A self-contained and self-explanatory DNA storage system
title_full_unstemmed	A self-contained and self-explanatory DNA storage system
title_sort	self-contained and self-explanatory dna storage system
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/dd599b22476a4bb98bbe91e9276329a7
work_keys_str_mv	AT minli aselfcontainedandselfexplanatorydnastoragesystem AT jiashuwu aselfcontainedandselfexplanatorydnastoragesystem AT junbiaodai aselfcontainedandselfexplanatorydnastoragesystem AT qingshanjiang aselfcontainedandselfexplanatorydnastoragesystem AT qiangqu aselfcontainedandselfexplanatorydnastoragesystem AT xiaoluohuang aselfcontainedandselfexplanatorydnastoragesystem AT yangwang aselfcontainedandselfexplanatorydnastoragesystem AT minli selfcontainedandselfexplanatorydnastoragesystem AT jiashuwu selfcontainedandselfexplanatorydnastoragesystem AT junbiaodai selfcontainedandselfexplanatorydnastoragesystem AT qingshanjiang selfcontainedandselfexplanatorydnastoragesystem AT qiangqu selfcontainedandselfexplanatorydnastoragesystem AT xiaoluohuang selfcontainedandselfexplanatorydnastoragesystem AT yangwang selfcontainedandselfexplanatorydnastoragesystem
_version_	1718381054171021312

A self-contained and self-explanatory DNA storage system

Ejemplares similares