Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway

Porcine epidemic diarrhoea virus (PEDV) infection causes watery diarrhoea, vomiting, anorexia, and weight loss, especially among neonatal piglets, inflicting on them morbidity and mortality potentially reaching 90%–100%. Despite it being known that certain mammalian cell phases are arrested by PEDV,...

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Autores principales:	Luo Yi-Ran, Zhou Shu-Ting, Yang Liang, Liu Yuan-Ping, Jiang Sheng-Yao, Dawuli Yeliboli, Hou Yi-Xuan, Zhou Tian-Xing, Yang Zhi-Biao
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2020
Materias:	porcine epidemic diarrhoea virus cell cycle virus proliferation dna damage signalling pathways Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/dd5c5fc585d34409bb9554a8163c5e1f
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spelling	oai:doaj.org-article:dd5c5fc585d34409bb9554a8163c5e1f2021-12-05T14:11:08ZPorcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway2450-860810.2478/jvetres-2020-0024https://doaj.org/article/dd5c5fc585d34409bb9554a8163c5e1f2020-03-01T00:00:00Zhttps://doi.org/10.2478/jvetres-2020-0024https://doaj.org/toc/2450-8608Porcine epidemic diarrhoea virus (PEDV) infection causes watery diarrhoea, vomiting, anorexia, and weight loss, especially among neonatal piglets, inflicting on them morbidity and mortality potentially reaching 90%–100%. Despite it being known that certain mammalian cell phases are arrested by PEDV, the mechanisms have not been elucidated, and PEDV pathogenesis is poorly understood. This study determined the effect of an epidemic PEDV strain on cell cycle progression.Luo Yi-RanZhou Shu-TingYang LiangLiu Yuan-PingJiang Sheng-YaoDawuli YeliboliHou Yi-XuanZhou Tian-XingYang Zhi-BiaoSciendoarticleporcine epidemic diarrhoea viruscell cyclevirus proliferationdna damagesignalling pathwaysVeterinary medicineSF600-1100ENJournal of Veterinary Research, Vol 64, Iss 1, Pp 25-32 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	porcine epidemic diarrhoea virus cell cycle virus proliferation dna damage signalling pathways Veterinary medicine SF600-1100
spellingShingle	porcine epidemic diarrhoea virus cell cycle virus proliferation dna damage signalling pathways Veterinary medicine SF600-1100 Luo Yi-Ran Zhou Shu-Ting Yang Liang Liu Yuan-Ping Jiang Sheng-Yao Dawuli Yeliboli Hou Yi-Xuan Zhou Tian-Xing Yang Zhi-Biao Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway
description	Porcine epidemic diarrhoea virus (PEDV) infection causes watery diarrhoea, vomiting, anorexia, and weight loss, especially among neonatal piglets, inflicting on them morbidity and mortality potentially reaching 90%–100%. Despite it being known that certain mammalian cell phases are arrested by PEDV, the mechanisms have not been elucidated, and PEDV pathogenesis is poorly understood. This study determined the effect of an epidemic PEDV strain on cell cycle progression.
format	article
author	Luo Yi-Ran Zhou Shu-Ting Yang Liang Liu Yuan-Ping Jiang Sheng-Yao Dawuli Yeliboli Hou Yi-Xuan Zhou Tian-Xing Yang Zhi-Biao
author_facet	Luo Yi-Ran Zhou Shu-Ting Yang Liang Liu Yuan-Ping Jiang Sheng-Yao Dawuli Yeliboli Hou Yi-Xuan Zhou Tian-Xing Yang Zhi-Biao
author_sort	Luo Yi-Ran
title	Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway
title_short	Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway
title_full	Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway
title_fullStr	Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway
title_full_unstemmed	Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway
title_sort	porcine epidemic diarrhoea virus induces cell-cycle arrest through the dna damage-signalling pathway
publisher	Sciendo
publishDate	2020
url	https://doaj.org/article/dd5c5fc585d34409bb9554a8163c5e1f
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Porcine epidemic diarrhoea virus induces cell-cycle arrest through the DNA damage-signalling pathway

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