Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches

Plant polyphenols are the main category of natural active substances, and are distributed widely in vegetables, fruits, and plant-based processed foods. Polyphenols have a beneficial performance in preventing diseases and maintaining body health. However, its action mechanism has not been well under...

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Autores principales: Wenjin Si, Yangdong Zhang, Xiang Li, Yufeng Du, Qingbiao Xu
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/dd67d7c5c6464fd7bacd4193ef5d6807
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spelling oai:doaj.org-article:dd67d7c5c6464fd7bacd4193ef5d68072021-11-25T18:35:34ZUnderstanding the Functional Activity of Polyphenols Using Omics-Based Approaches10.3390/nu131139532072-6643https://doaj.org/article/dd67d7c5c6464fd7bacd4193ef5d68072021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3953https://doaj.org/toc/2072-6643Plant polyphenols are the main category of natural active substances, and are distributed widely in vegetables, fruits, and plant-based processed foods. Polyphenols have a beneficial performance in preventing diseases and maintaining body health. However, its action mechanism has not been well understood. Foodomics is a novel method to sequence and widely used in nutrition, combining genomics, proteomics, transcriptomics, microbiome, and metabolomics. Based on multi-omics technologies, foodomics provides abundant data to study functional activities of polyphenols. In this paper, physiological functions of various polyphenols based on foodomics and microbiome was discussed, especially the anti-inflammatory and anti-tumor activities and gut microbe regulation. In conclusion, omics (including microbiomics) is a useful approach to explore the bioactive activities of polyphenols in the nutrition and health of human and animals.Wenjin SiYangdong ZhangXiang LiYufeng DuQingbiao XuMDPI AGarticlepolyphenolsfoodomicsfunctional activitygut microbiotamulti-omicsNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3953, p 3953 (2021)
institution DOAJ
collection DOAJ
language EN
topic polyphenols
foodomics
functional activity
gut microbiota
multi-omics
Nutrition. Foods and food supply
TX341-641
spellingShingle polyphenols
foodomics
functional activity
gut microbiota
multi-omics
Nutrition. Foods and food supply
TX341-641
Wenjin Si
Yangdong Zhang
Xiang Li
Yufeng Du
Qingbiao Xu
Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches
description Plant polyphenols are the main category of natural active substances, and are distributed widely in vegetables, fruits, and plant-based processed foods. Polyphenols have a beneficial performance in preventing diseases and maintaining body health. However, its action mechanism has not been well understood. Foodomics is a novel method to sequence and widely used in nutrition, combining genomics, proteomics, transcriptomics, microbiome, and metabolomics. Based on multi-omics technologies, foodomics provides abundant data to study functional activities of polyphenols. In this paper, physiological functions of various polyphenols based on foodomics and microbiome was discussed, especially the anti-inflammatory and anti-tumor activities and gut microbe regulation. In conclusion, omics (including microbiomics) is a useful approach to explore the bioactive activities of polyphenols in the nutrition and health of human and animals.
format article
author Wenjin Si
Yangdong Zhang
Xiang Li
Yufeng Du
Qingbiao Xu
author_facet Wenjin Si
Yangdong Zhang
Xiang Li
Yufeng Du
Qingbiao Xu
author_sort Wenjin Si
title Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches
title_short Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches
title_full Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches
title_fullStr Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches
title_full_unstemmed Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches
title_sort understanding the functional activity of polyphenols using omics-based approaches
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/dd67d7c5c6464fd7bacd4193ef5d6807
work_keys_str_mv AT wenjinsi understandingthefunctionalactivityofpolyphenolsusingomicsbasedapproaches
AT yangdongzhang understandingthefunctionalactivityofpolyphenolsusingomicsbasedapproaches
AT xiangli understandingthefunctionalactivityofpolyphenolsusingomicsbasedapproaches
AT yufengdu understandingthefunctionalactivityofpolyphenolsusingomicsbasedapproaches
AT qingbiaoxu understandingthefunctionalactivityofpolyphenolsusingomicsbasedapproaches
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