Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes

Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes

Plasmodium vivax biology is not well understood, due to a lack of in vitro culture systems and difficulties associated with studying clinical blood samples. Here, Kim et al. use gene expression profiles from P. vivax infected patient blood and show stage-specific chloroquine response and differentia...

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Autores principales: Adam Kim, Jean Popovici, Didier Menard, David Serre
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/dd68ed0408f6443b81edead0762457ba
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spelling oai:doaj.org-article:dd68ed0408f6443b81edead0762457ba2021-12-02T17:33:23ZPlasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes10.1038/s41467-019-08312-z2041-1723https://doaj.org/article/dd68ed0408f6443b81edead0762457ba2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08312-zhttps://doaj.org/toc/2041-1723Plasmodium vivax biology is not well understood, due to a lack of in vitro culture systems and difficulties associated with studying clinical blood samples. Here, Kim et al. use gene expression profiles from P. vivax infected patient blood and show stage-specific chloroquine response and differential regulation of male and female gametocytes.Adam KimJean PopoviciDidier MenardDavid SerreNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Adam Kim
Jean Popovici
Didier Menard
David Serre
Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
description Plasmodium vivax biology is not well understood, due to a lack of in vitro culture systems and difficulties associated with studying clinical blood samples. Here, Kim et al. use gene expression profiles from P. vivax infected patient blood and show stage-specific chloroquine response and differential regulation of male and female gametocytes.
format article
author Adam Kim
Jean Popovici
Didier Menard
David Serre
author_facet Adam Kim
Jean Popovici
Didier Menard
David Serre
author_sort Adam Kim
title Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
title_short Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
title_full Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
title_fullStr Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
title_full_unstemmed Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
title_sort plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/dd68ed0408f6443b81edead0762457ba
work_keys_str_mv AT adamkim plasmodiumvivaxtranscriptomesrevealstagespecificchloroquineresponseanddifferentialregulationofmaleandfemalegametocytes
AT jeanpopovici plasmodiumvivaxtranscriptomesrevealstagespecificchloroquineresponseanddifferentialregulationofmaleandfemalegametocytes
AT didiermenard plasmodiumvivaxtranscriptomesrevealstagespecificchloroquineresponseanddifferentialregulationofmaleandfemalegametocytes
AT davidserre plasmodiumvivaxtranscriptomesrevealstagespecificchloroquineresponseanddifferentialregulationofmaleandfemalegametocytes
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