Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles

Tetsuya Muto, Shigeki Machida Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, JapanCorrespondence: Tetsuya MutoDepartment of Ophthalmology, Dokkyo Medical UniversitySaitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya 343-8555, JapanTel +81 48 965 1111F...

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Autores principales:	Muto T, Machida S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	aflibercept intravitreal injection vitreous reflux intraocular pressure Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/dd6a5794f628441787dc104d22812017
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spelling	oai:doaj.org-article:dd6a5794f628441787dc104d228120172021-12-02T08:29:52ZVitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles1177-5483https://doaj.org/article/dd6a5794f628441787dc104d228120172020-03-01T00:00:00Zhttps://www.dovepress.com/vitreous-reflux-frequency-and-intraocular-pressure-after-first-time-in-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Tetsuya Muto, Shigeki Machida Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, JapanCorrespondence: Tetsuya MutoDepartment of Ophthalmology, Dokkyo Medical UniversitySaitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya 343-8555, JapanTel +81 48 965 1111Fax +81 48 965 1127Email ueda.castle@gmail.comPurpose: To compare the effects of 30-gauge versus 32-gauge needles on vitreous reflux (VR) frequency and intraocular pressure (IOP) following first-time intravitreal aflibercept injections.Materials and Methods: Overall, 116 patients (116 eyes) who received intravitreal injections using 30-gauge needles and 104 patients (104 eyes) who received the same injection using 32-gauge needles were reviewed. The medical records of 116 patients who each received an intravitreal injection using a 30-gauge needle (median age: 67.5 ± 13.9 years) and 104 patients who each received the same injection using a 32-gauge needle (median age: 66. 3 ± 10.6 years) from January 2015 to June 2019 were compared.Results: No significant difference in the frequency of VR was observed between patients injected using 30-gauge needles (38/116) and patients injected using 32-gauge needles (31/104, P = 0.64). There were no significant differences in the VR rates of patients with phakic and pseudophakic eyes between those injected using 30-gauge (P = 0.94) or 32-gauge needles (P = 0.77). Axial length did not significantly differ between patients with and without VR when injected using 30-gauge (P = 0.89) and with 32-gauge needles (P = 0.69). IOP immediately after injection was significantly higher in patients injected using 30-gauge needles than in patients injected using 32-gauge needles (P < 0.01).Conclusion: VR frequency was not correlated with needle size, lens status, or axial length. Patients receiving injections using 30-gauge needles had higher IOP immediately after intravitreal injection.Keywords: aflibercept, intravitreal injection, vitreous reflux, intraocular pressureMuto TMachida SDove Medical Pressarticleafliberceptintravitreal injectionvitreous refluxintraocular pressureOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 625-634 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	aflibercept intravitreal injection vitreous reflux intraocular pressure Ophthalmology RE1-994
spellingShingle	aflibercept intravitreal injection vitreous reflux intraocular pressure Ophthalmology RE1-994 Muto T Machida S Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles
description	Tetsuya Muto, Shigeki Machida Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, JapanCorrespondence: Tetsuya MutoDepartment of Ophthalmology, Dokkyo Medical UniversitySaitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya 343-8555, JapanTel +81 48 965 1111Fax +81 48 965 1127Email ueda.castle@gmail.comPurpose: To compare the effects of 30-gauge versus 32-gauge needles on vitreous reflux (VR) frequency and intraocular pressure (IOP) following first-time intravitreal aflibercept injections.Materials and Methods: Overall, 116 patients (116 eyes) who received intravitreal injections using 30-gauge needles and 104 patients (104 eyes) who received the same injection using 32-gauge needles were reviewed. The medical records of 116 patients who each received an intravitreal injection using a 30-gauge needle (median age: 67.5 ± 13.9 years) and 104 patients who each received the same injection using a 32-gauge needle (median age: 66. 3 ± 10.6 years) from January 2015 to June 2019 were compared.Results: No significant difference in the frequency of VR was observed between patients injected using 30-gauge needles (38/116) and patients injected using 32-gauge needles (31/104, P = 0.64). There were no significant differences in the VR rates of patients with phakic and pseudophakic eyes between those injected using 30-gauge (P = 0.94) or 32-gauge needles (P = 0.77). Axial length did not significantly differ between patients with and without VR when injected using 30-gauge (P = 0.89) and with 32-gauge needles (P = 0.69). IOP immediately after injection was significantly higher in patients injected using 30-gauge needles than in patients injected using 32-gauge needles (P < 0.01).Conclusion: VR frequency was not correlated with needle size, lens status, or axial length. Patients receiving injections using 30-gauge needles had higher IOP immediately after intravitreal injection.Keywords: aflibercept, intravitreal injection, vitreous reflux, intraocular pressure
format	article
author	Muto T Machida S
author_facet	Muto T Machida S
author_sort	Muto T
title	Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles
title_short	Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles
title_full	Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles
title_fullStr	Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles
title_full_unstemmed	Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles
title_sort	vitreous reflux frequency and intraocular pressure after first-time intravitreal aflibercept injections: comparison of 30- and 32-gauge needles
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/dd6a5794f628441787dc104d22812017
work_keys_str_mv	AT mutot vitreousrefluxfrequencyandintraocularpressureafterfirsttimeintravitrealafliberceptinjectionscomparisonof30and32gaugeneedles AT machidas vitreousrefluxfrequencyandintraocularpressureafterfirsttimeintravitrealafliberceptinjectionscomparisonof30and32gaugeneedles
_version_	1718398513369317376

Vitreous Reflux Frequency and Intraocular Pressure After First-Time Intravitreal Aflibercept Injections: Comparison of 30- and 32-Gauge Needles

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