Pd-catalyzed enantioselective intramolecular Heck reaction to access disubstituted dihydroisoquinolinone with a terminal olefin

A first palladium-catalyzed asymmetric intramolecular Heck reaction for the construction 3,4-dihydro-1-(2H)-isoquinolinone containing the quaternary carbon chiral center has been developed. The salient features of this reaction include high efficiency, high enantioselectivity, the novel chiral ligan...

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Auteurs principaux: Sanliang Li, Qiaoyu Chen, Zhan-Ming Zhang, Junliang Zhang
Format: article
Langue:EN
Publié: KeAi Communications Co. Ltd. 2021
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Accès en ligne:https://doaj.org/article/dd732803d4564fb7916cd1148cefcfa4
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