Pd-catalyzed enantioselective intramolecular Heck reaction to access disubstituted dihydroisoquinolinone with a terminal olefin
A first palladium-catalyzed asymmetric intramolecular Heck reaction for the construction 3,4-dihydro-1-(2H)-isoquinolinone containing the quaternary carbon chiral center has been developed. The salient features of this reaction include high efficiency, high enantioselectivity, the novel chiral ligan...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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KeAi Communications Co. Ltd.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/dd732803d4564fb7916cd1148cefcfa4 |
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