The heterogeneity of megakaryocytes and platelets and implications for ex vivo platelet generation

Abstract Platelets, the chief effector of hemostasis, are small anucleate blood cells generated from megakaryocytes (MKs), and the defects in platelet production or function lead to a variety of bleeding complications. Emerging evidence indicates that MKs and platelets are much more diverse than pre...

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Auteurs principaux: Cuicui Liu, Baiming Huang, Hongtao Wang, Jiaxi Zhou
Format: article
Langue:EN
Publié: Wiley 2021
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Accès en ligne:https://doaj.org/article/dd78647a8b37494daa94229ba6ffd25f
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