easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.
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Nature Portfolio
2021
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oai:doaj.org-article:dd96eec6ff1a4e01a51eb5bbd511fef72021-12-02T13:34:29ZeasyCLIP analysis of RNA-protein interactions incorporating absolute quantification10.1038/s41467-021-21623-42041-1723https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef72021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21623-4https://doaj.org/toc/2041-1723It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.Douglas F. PorterWeili MiaoXue YangGrant A. GodaAndrew L. JiLaura K. H. DonohueMaria M. AlemanDaniel DominguezPaul A. KhavariNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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Science Q Douglas F. Porter Weili Miao Xue Yang Grant A. Goda Andrew L. Ji Laura K. H. Donohue Maria M. Aleman Daniel Dominguez Paul A. Khavari easyCLIP analysis of RNA-protein interactions incorporating absolute quantification |
description |
It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins. |
format |
article |
author |
Douglas F. Porter Weili Miao Xue Yang Grant A. Goda Andrew L. Ji Laura K. H. Donohue Maria M. Aleman Daniel Dominguez Paul A. Khavari |
author_facet |
Douglas F. Porter Weili Miao Xue Yang Grant A. Goda Andrew L. Ji Laura K. H. Donohue Maria M. Aleman Daniel Dominguez Paul A. Khavari |
author_sort |
Douglas F. Porter |
title |
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification |
title_short |
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification |
title_full |
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification |
title_fullStr |
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification |
title_full_unstemmed |
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification |
title_sort |
easyclip analysis of rna-protein interactions incorporating absolute quantification |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef7 |
work_keys_str_mv |
AT douglasfporter easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT weilimiao easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT xueyang easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT grantagoda easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT andrewlji easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT laurakhdonohue easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT mariamaleman easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT danieldominguez easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT paulakhavari easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification |
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