easyCLIP analysis of RNA-protein interactions incorporating absolute quantification

It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.

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Auteurs principaux:	Douglas F. Porter, Weili Miao, Xue Yang, Grant A. Goda, Andrew L. Ji, Laura K. H. Donohue, Maria M. Aleman, Daniel Dominguez, Paul A. Khavari
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef7
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spelling	oai:doaj.org-article:dd96eec6ff1a4e01a51eb5bbd511fef72021-12-02T13:34:29ZeasyCLIP analysis of RNA-protein interactions incorporating absolute quantification10.1038/s41467-021-21623-42041-1723https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef72021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21623-4https://doaj.org/toc/2041-1723It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.Douglas F. PorterWeili MiaoXue YangGrant A. GodaAndrew L. JiLaura K. H. DonohueMaria M. AlemanDaniel DominguezPaul A. KhavariNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Douglas F. Porter Weili Miao Xue Yang Grant A. Goda Andrew L. Ji Laura K. H. Donohue Maria M. Aleman Daniel Dominguez Paul A. Khavari easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
description	It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.
format	article
author	Douglas F. Porter Weili Miao Xue Yang Grant A. Goda Andrew L. Ji Laura K. H. Donohue Maria M. Aleman Daniel Dominguez Paul A. Khavari
author_facet	Douglas F. Porter Weili Miao Xue Yang Grant A. Goda Andrew L. Ji Laura K. H. Donohue Maria M. Aleman Daniel Dominguez Paul A. Khavari
author_sort	Douglas F. Porter
title	easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_short	easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_full	easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_fullStr	easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_full_unstemmed	easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_sort	easyclip analysis of rna-protein interactions incorporating absolute quantification
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef7
work_keys_str_mv	AT douglasfporter easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT weilimiao easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT xueyang easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT grantagoda easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT andrewlji easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT laurakhdonohue easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT mariamaleman easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT danieldominguez easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification AT paulakhavari easyclipanalysisofrnaproteininteractionsincorporatingabsolutequantification
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easyCLIP analysis of RNA-protein interactions incorporating absolute quantification

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