easyCLIP analysis of RNA-protein interactions incorporating absolute quantification

It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.

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Autores principales: Douglas F. Porter, Weili Miao, Xue Yang, Grant A. Goda, Andrew L. Ji, Laura K. H. Donohue, Maria M. Aleman, Daniel Dominguez, Paul A. Khavari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef7
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spelling oai:doaj.org-article:dd96eec6ff1a4e01a51eb5bbd511fef72021-12-02T13:34:29ZeasyCLIP analysis of RNA-protein interactions incorporating absolute quantification10.1038/s41467-021-21623-42041-1723https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef72021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21623-4https://doaj.org/toc/2041-1723It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.Douglas F. PorterWeili MiaoXue YangGrant A. GodaAndrew L. JiLaura K. H. DonohueMaria M. AlemanDaniel DominguezPaul A. KhavariNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Douglas F. Porter
Weili Miao
Xue Yang
Grant A. Goda
Andrew L. Ji
Laura K. H. Donohue
Maria M. Aleman
Daniel Dominguez
Paul A. Khavari
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
description It is important to develop quantitative criteria to identify RNA-binding proteins and target RNAs. Here, the authors present a method to quantify cross-linking and apply it to recurrent cancer mutations in RNA-binding proteins.
format article
author Douglas F. Porter
Weili Miao
Xue Yang
Grant A. Goda
Andrew L. Ji
Laura K. H. Donohue
Maria M. Aleman
Daniel Dominguez
Paul A. Khavari
author_facet Douglas F. Porter
Weili Miao
Xue Yang
Grant A. Goda
Andrew L. Ji
Laura K. H. Donohue
Maria M. Aleman
Daniel Dominguez
Paul A. Khavari
author_sort Douglas F. Porter
title easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_short easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_full easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_fullStr easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_full_unstemmed easyCLIP analysis of RNA-protein interactions incorporating absolute quantification
title_sort easyclip analysis of rna-protein interactions incorporating absolute quantification
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/dd96eec6ff1a4e01a51eb5bbd511fef7
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