Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.

Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.

<h4>Background</h4>Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-beta (Abeta) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-li...

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Main Authors: Thomas Walther, Doris Albrecht, Matthias Becker, Manja Schubert, Elena Kouznetsova, Burkard Wiesner, Björn Maul, Reinhard Schliebs, Gisela Grecksch, Jens Furkert, Anja Sterner-Kock, Heinz-Peter Schultheiss, Axel Becker, Wolf-Eberhard Siems
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/dd9c715bc1034a5fa52e7b851539303a
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https://doaj.org/article/dd9c715bc1034a5fa52e7b851539303a

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