Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.
<h4>Background</h4>Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-beta (Abeta) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-li...
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Autores principales: | Thomas Walther, Doris Albrecht, Matthias Becker, Manja Schubert, Elena Kouznetsova, Burkard Wiesner, Björn Maul, Reinhard Schliebs, Gisela Grecksch, Jens Furkert, Anja Sterner-Kock, Heinz-Peter Schultheiss, Axel Becker, Wolf-Eberhard Siems |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/dd9c715bc1034a5fa52e7b851539303a |
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