Metabolic Engineering of Microorganisms for the Production of Higher Alcohols

ABSTRACT Due to the increasing concerns about limited fossil resources and environmental problems, there has been much interest in developing biofuels from renewable biomass. Ethanol is currently used as a major biofuel, as it can be easily produced by existing fermentation technology, but it is not...

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Autores principales:	Yong Jun Choi, Joungmin Lee, Yu-Sin Jang, Sang Yup Lee
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2014
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/dda1257d85164deba3b4f4269b468cdc
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spelling	oai:doaj.org-article:dda1257d85164deba3b4f4269b468cdc2021-11-15T15:45:55ZMetabolic Engineering of Microorganisms for the Production of Higher Alcohols10.1128/mBio.01524-142150-7511https://doaj.org/article/dda1257d85164deba3b4f4269b468cdc2014-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01524-14https://doaj.org/toc/2150-7511ABSTRACT Due to the increasing concerns about limited fossil resources and environmental problems, there has been much interest in developing biofuels from renewable biomass. Ethanol is currently used as a major biofuel, as it can be easily produced by existing fermentation technology, but it is not the best biofuel due to its low energy density, high vapor pressure, hygroscopy, and incompatibility with current infrastructure. Higher alcohols, including 1-propanol, 1-butanol, isobutanol, 2-methyl-1-butanol, and 3-methyl-1-butanol, which possess fuel properties more similar to those of petroleum-based fuel, have attracted particular interest as alternatives to ethanol. Since microorganisms isolated from nature do not allow production of these alcohols at high enough efficiencies, metabolic engineering has been employed to enhance their production. Here, we review recent advances in metabolic engineering of microorganisms for the production of higher alcohols.Yong Jun ChoiJoungmin LeeYu-Sin JangSang Yup LeeAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 5, Iss 5 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Yong Jun Choi Joungmin Lee Yu-Sin Jang Sang Yup Lee Metabolic Engineering of Microorganisms for the Production of Higher Alcohols
description	ABSTRACT Due to the increasing concerns about limited fossil resources and environmental problems, there has been much interest in developing biofuels from renewable biomass. Ethanol is currently used as a major biofuel, as it can be easily produced by existing fermentation technology, but it is not the best biofuel due to its low energy density, high vapor pressure, hygroscopy, and incompatibility with current infrastructure. Higher alcohols, including 1-propanol, 1-butanol, isobutanol, 2-methyl-1-butanol, and 3-methyl-1-butanol, which possess fuel properties more similar to those of petroleum-based fuel, have attracted particular interest as alternatives to ethanol. Since microorganisms isolated from nature do not allow production of these alcohols at high enough efficiencies, metabolic engineering has been employed to enhance their production. Here, we review recent advances in metabolic engineering of microorganisms for the production of higher alcohols.
format	article
author	Yong Jun Choi Joungmin Lee Yu-Sin Jang Sang Yup Lee
author_facet	Yong Jun Choi Joungmin Lee Yu-Sin Jang Sang Yup Lee
author_sort	Yong Jun Choi
title	Metabolic Engineering of Microorganisms for the Production of Higher Alcohols
title_short	Metabolic Engineering of Microorganisms for the Production of Higher Alcohols
title_full	Metabolic Engineering of Microorganisms for the Production of Higher Alcohols
title_fullStr	Metabolic Engineering of Microorganisms for the Production of Higher Alcohols
title_full_unstemmed	Metabolic Engineering of Microorganisms for the Production of Higher Alcohols
title_sort	metabolic engineering of microorganisms for the production of higher alcohols
publisher	American Society for Microbiology
publishDate	2014
url	https://doaj.org/article/dda1257d85164deba3b4f4269b468cdc
work_keys_str_mv	AT yongjunchoi metabolicengineeringofmicroorganismsfortheproductionofhigheralcohols AT joungminlee metabolicengineeringofmicroorganismsfortheproductionofhigheralcohols AT yusinjang metabolicengineeringofmicroorganismsfortheproductionofhigheralcohols AT sangyuplee metabolicengineeringofmicroorganismsfortheproductionofhigheralcohols
_version_	1718427552897302528

Metabolic Engineering of Microorganisms for the Production of Higher Alcohols

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