An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction, but conformational changes associated with gating remained unknown. Here authors use high-speed atomic force microscopy to visualize SthK channels dynamics in response to cyclic nucleotides.

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Autores principales:	Arin Marchesi, Xiaolong Gao, Ricardo Adaixo, Jan Rheinberger, Henning Stahlberg, Crina Nimigean, Simon Scheuring
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dda37f7ba8ad44b1bbc12e9cfdef05d2
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spelling	oai:doaj.org-article:dda37f7ba8ad44b1bbc12e9cfdef05d22021-12-02T15:34:05ZAn iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel10.1038/s41467-018-06414-82041-1723https://doaj.org/article/dda37f7ba8ad44b1bbc12e9cfdef05d22018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06414-8https://doaj.org/toc/2041-1723Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction, but conformational changes associated with gating remained unknown. Here authors use high-speed atomic force microscopy to visualize SthK channels dynamics in response to cyclic nucleotides.Arin MarchesiXiaolong GaoRicardo AdaixoJan RheinbergerHenning StahlbergCrina NimigeanSimon ScheuringNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Arin Marchesi Xiaolong Gao Ricardo Adaixo Jan Rheinberger Henning Stahlberg Crina Nimigean Simon Scheuring An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
description	Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction, but conformational changes associated with gating remained unknown. Here authors use high-speed atomic force microscopy to visualize SthK channels dynamics in response to cyclic nucleotides.
format	article
author	Arin Marchesi Xiaolong Gao Ricardo Adaixo Jan Rheinberger Henning Stahlberg Crina Nimigean Simon Scheuring
author_facet	Arin Marchesi Xiaolong Gao Ricardo Adaixo Jan Rheinberger Henning Stahlberg Crina Nimigean Simon Scheuring
author_sort	Arin Marchesi
title	An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
title_short	An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
title_full	An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
title_fullStr	An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
title_full_unstemmed	An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
title_sort	iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/dda37f7ba8ad44b1bbc12e9cfdef05d2
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An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

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