Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer
Abstract Hyperactivation of Wnt and Ras-MAPK signalling are common events in development of colorectal adenomas. Further progression from adenoma-to-carcinoma is frequently associated with 20q gain and overexpression of Aurora kinase A (AURKA). Interestingly, AURKA has been shown to further enhance...
Enregistré dans:
Auteurs principaux: | Annika Jacobsen, Linda J. W. Bosch, Sanne R. Martens-de Kemp, Beatriz Carvalho, Anke H. Sillars-Hardebol, Richard J. Dobson, Emanuele de Rinaldis, Gerrit A. Meijer, Sanne Abeln, Jaap Heringa, Remond J. A. Fijneman, K. Anton Feenstra |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/dda70b65d4554e6cb45b72de811ecbd1 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Disordered flanks prevent peptide aggregation.
par: Sanne Abeln, et autres
Publié: (2008) -
Clinical Translation of Combined MAPK and Autophagy Inhibition in <i>RAS</i> Mutant Cancer
par: Jennifer J. Lee, et autres
Publié: (2021) -
Acrolein contributes to human colorectal tumorigenesis through the activation of RAS-MAPK pathway
par: Hong-Chieh Tsai, et autres
Publié: (2021) -
Exploring fold space preferences of new-born and ancient protein superfamilies.
par: Hannah Edwards, et autres
Publié: (2013) -
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
par: Silke Pudewell, et autres
Publié: (2021)