KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation
Genomic loops and their temporal dynamics play an important role in gene expression of DNA viruses, but are incompletely understood. Here, the authors use capture Hi-C analyses and identify genomic architectural dynamics of KSHV that are regulated by the viral transactivator K-Rta.
Guardado en:
Autores principales: | Mel Campbell, Tadashi Watanabe, Kazushi Nakano, Ryan R. Davis, Yuanzhi Lyu, Clifford G. Tepper, Blythe Durbin-Johnson, Masahiro Fujimuro, Yoshihiro Izumiya |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/dda9944922624a1d8b1fe07d7ee176f6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth
por: Michiko Shimoda, et al.
Publicado: (2021) -
Latently KSHV-Infected Cells Promote Further Establishment of Latency upon Superinfection with KSHV
por: Chen Gam ze Letova, et al.
Publicado: (2021) -
Pax5 mediates the transcriptional activation of the CD81 gene
por: Kohei Hosokawa, et al.
Publicado: (2021) -
Eco-Evolutionary Dynamics of Episomes among Ecologically Cohesive Bacterial Populations
por: Hong Xue, et al.
Publicado: (2015) -
An Episomal CRISPR/Cas12a System for Mediating Efficient Gene Editing
por: Nannan Duan, et al.
Publicado: (2021)