The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of <italic toggle="yes">Helicobacter pylori</italic> in Neutrophils

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of <italic toggle="yes">Helicobacter pylori</italic> in Neutrophils

ABSTRACT The cag type IV secretion system (cag-T4SS) of Helicobacter pylori exploits specific cellular carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), such as CEACAM1, -3, -5, and -6, as cellular receptors for CagA translocation into human gastric epithelial cells. We studied the...

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Autores principales: Ina-Kristin Behrens, Benjamin Busch, Hellen Ishikawa-Ankerhold, Pia Palamides, John E. Shively, Cliff Stanners, Carlos Chan, Nelly Leung, Scott Gray-Owen, Rainer Haas
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Helicobacter pylori
cag-type IV secretion system
CagA translocation
tyrosine-phosphorylation
phagocytosis
neutrophils
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ddb179f2f9174e459c0be8f3bc5d3a80
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