Modulation of RNA primer formation by Mn(II)-substituted T7 DNA primase
Abstract Lagging strand DNA synthesis by DNA polymerase requires RNA primers produced by DNA primase. The N-terminal primase domain of the gene 4 protein of phage T7 comprises a zinc-binding domain that recognizes a specific DNA sequence and an RNA polymerase domain that catalyzes RNA polymerization...
Guardado en:
Autores principales: | Stefan Ilic, Sabine R. Akabayov, Roy Froimovici, Ron Meiry, Dan Vilenchik, Alfredo Hernandez, Haribabu Arthanari, Barak Akabayov |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ddb5b468f6e24d28a55bdb8dbaddae94 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster
por: Sandro Holzer, et al.
Publicado: (2017) -
Pol α-primase dependent nuclear localization of the mammalian CST complex
por: Joseph M. Kelich, et al.
Publicado: (2021) -
CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation
por: Katerina Zabrady, et al.
Publicado: (2021) -
Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria
por: Yingqin Zhou, et al.
Publicado: (2017) -
Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C
por: Nigel C. Brissett, et al.
Publicado: (2020)