Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives

Miles B Markus1,2 1School of Animal, Plant and Environmental Sciences, Faculty of Science, University of the Witwatersrand, Johannesburg, South Africa; 2Wits Research Institute for Malaria, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaCo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Markus MB
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	chloroquine g6pd hypnozoite primaquine relapse wr238605 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/ddbd7634b2574c9cba0ec100a8528987
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ddbd7634b2574c9cba0ec100a8528987
record_format	dspace
spelling	oai:doaj.org-article:ddbd7634b2574c9cba0ec100a85289872021-12-02T14:57:24ZSafety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives1178-203Xhttps://doaj.org/article/ddbd7634b2574c9cba0ec100a85289872021-09-01T00:00:00Zhttps://www.dovepress.com/safety-and-efficacy-of-tafenoquine-for-plasmodium-vivax-malaria-prophy-peer-reviewed-fulltext-article-TCRMhttps://doaj.org/toc/1178-203XMiles B Markus1,2 1School of Animal, Plant and Environmental Sciences, Faculty of Science, University of the Witwatersrand, Johannesburg, South Africa; 2Wits Research Institute for Malaria, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence: Miles B MarkusWits Research Institute for Malaria, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South AfricaTel +27 794580773Fax +27 117892950Email medsynth@yahoo.co.ukAbstract: This article is inter alia a brief, first-stop guide to possible adverse events (AEs) associated with tafenoquine (TQ) intake. Safety and efficacy findings for TQ in Plasmodium vivax malaria prophylaxis and radical cure are summarized and some of the latest TQ-related studies (published in 2020 and 2021) are highlighted. In addition, little-known biological and other matters concerning malaria parasites and 8-aminoquinoline (8-AQ) drug action are discussed and some correct terminology pertinent to malaria is explained.Keywords: chloroquine, G6PD, hypnozoite, primaquine, relapse, WR238605Markus MBDove Medical Pressarticlechloroquineg6pdhypnozoiteprimaquinerelapsewr238605Therapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 989-999 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chloroquine g6pd hypnozoite primaquine relapse wr238605 Therapeutics. Pharmacology RM1-950
spellingShingle	chloroquine g6pd hypnozoite primaquine relapse wr238605 Therapeutics. Pharmacology RM1-950 Markus MB Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives
description	Miles B Markus1,2 1School of Animal, Plant and Environmental Sciences, Faculty of Science, University of the Witwatersrand, Johannesburg, South Africa; 2Wits Research Institute for Malaria, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence: Miles B MarkusWits Research Institute for Malaria, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South AfricaTel +27 794580773Fax +27 117892950Email medsynth@yahoo.co.ukAbstract: This article is inter alia a brief, first-stop guide to possible adverse events (AEs) associated with tafenoquine (TQ) intake. Safety and efficacy findings for TQ in Plasmodium vivax malaria prophylaxis and radical cure are summarized and some of the latest TQ-related studies (published in 2020 and 2021) are highlighted. In addition, little-known biological and other matters concerning malaria parasites and 8-aminoquinoline (8-AQ) drug action are discussed and some correct terminology pertinent to malaria is explained.Keywords: chloroquine, G6PD, hypnozoite, primaquine, relapse, WR238605
format	article
author	Markus MB
author_facet	Markus MB
author_sort	Markus MB
title	Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives
title_short	Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives
title_full	Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives
title_fullStr	Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives
title_full_unstemmed	Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives
title_sort	safety and efficacy of tafenoquine for plasmodium vivax malaria prophylaxis and radical cure: overview and perspectives
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/ddbd7634b2574c9cba0ec100a8528987
work_keys_str_mv	AT markusmb safetyandefficacyoftafenoquineforplasmodiumvivaxmalariaprophylaxisandradicalcureoverviewandperspectives
_version_	1718389355643404288

Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives

Ejemplares similares