Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori

The aim of the study was to examine the features of the endoscopic picture in the upper digestive tract mucosa in paediatric chronic gastroduodenal pathology (CGDP) associated with Helicobacter pylori. Materials and methods. There were examined 286 patients, aged 6–15 years. Diagnostic criteria for...

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Autores principales:	Sh. T. Turdieva, E. A. Shamansurova
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2020
Materias:	helicobacter pylori gastroduodenal pathology children adolescents chronic gastritis stomach ulcer Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/ddce371e11b64104b034b7541773b905
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spelling	oai:doaj.org-article:ddce371e11b64104b034b7541773b9052021-11-22T07:09:54ZFeatures of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori2220-76192313-739810.15789/2220-7619-FOT-1249https://doaj.org/article/ddce371e11b64104b034b7541773b9052020-08-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/1249https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398The aim of the study was to examine the features of the endoscopic picture in the upper digestive tract mucosa in paediatric chronic gastroduodenal pathology (CGDP) associated with Helicobacter pylori. Materials and methods. There were examined 286 patients, aged 6–15 years. Diagnostic criteria for chronic gastroduodenal pathology were anamnestic as well as instrumental and functional studies data: gastric fractional intubation, esophagogastroduodenoscopy (EPGDS) with endoscopic pH-metry without biopsy, and ultrasound examination of abdominal organs. H. pylori testing was carried out by two unrelated methods such as respiratory test and a immunochromatographic fecal test. Results. Detection of H. pylori in children with CGDP peaked in patients with peptic gastric and duodenal ulcer (up to 87.5%, p < 0.05). The main endoscopic signs were edema, hyperaemia and contact bleeding, as well as local haemorrhage were the major endoscopic signs of inflammation in the stomach and duodenum mucosa. Atrophic mucosal lesions were characterized by thinning, pale colour together with transilluminated submucosal vessels. Non-atrophic antral gastritis was featured with delayed gastric emptying, antral stasis and pyloric spasm. In contrast, hypotension of the gastric wall, duodenogastric reflux and decreased motility were more typical to chronic atrophic gastritis. Major endoscopic feature in patients with H. pylori infection was presented by dominant atrophic changes combined with gastroduodenal reflux (77.6%, p < 0.05) compared to patients without H. pylori infection. Conclusion. Detection of HP infection was peaked in children with CGDP coupled to peptic ulcer disease compared to patients with inflammatory diseases (p < 0.05). Endoscopic examination in HP-positive patients showed that atrophic changes were found by 4-fold more frequently together with gastroduodenal reflux compared to patients without HP infection (p < 0.05).Sh. T. TurdievaE. A. ShamansurovaSankt-Peterburg : NIIÈM imeni Pasteraarticlehelicobacter pylorigastroduodenal pathologychildrenadolescentschronic gastritisstomach ulcerInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 10, Iss 3, Pp 543-550 (2020)
institution	DOAJ
collection	DOAJ
language	RU
topic	helicobacter pylori gastroduodenal pathology children adolescents chronic gastritis stomach ulcer Infectious and parasitic diseases RC109-216
spellingShingle	helicobacter pylori gastroduodenal pathology children adolescents chronic gastritis stomach ulcer Infectious and parasitic diseases RC109-216 Sh. T. Turdieva E. A. Shamansurova Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori
description	The aim of the study was to examine the features of the endoscopic picture in the upper digestive tract mucosa in paediatric chronic gastroduodenal pathology (CGDP) associated with Helicobacter pylori. Materials and methods. There were examined 286 patients, aged 6–15 years. Diagnostic criteria for chronic gastroduodenal pathology were anamnestic as well as instrumental and functional studies data: gastric fractional intubation, esophagogastroduodenoscopy (EPGDS) with endoscopic pH-metry without biopsy, and ultrasound examination of abdominal organs. H. pylori testing was carried out by two unrelated methods such as respiratory test and a immunochromatographic fecal test. Results. Detection of H. pylori in children with CGDP peaked in patients with peptic gastric and duodenal ulcer (up to 87.5%, p < 0.05). The main endoscopic signs were edema, hyperaemia and contact bleeding, as well as local haemorrhage were the major endoscopic signs of inflammation in the stomach and duodenum mucosa. Atrophic mucosal lesions were characterized by thinning, pale colour together with transilluminated submucosal vessels. Non-atrophic antral gastritis was featured with delayed gastric emptying, antral stasis and pyloric spasm. In contrast, hypotension of the gastric wall, duodenogastric reflux and decreased motility were more typical to chronic atrophic gastritis. Major endoscopic feature in patients with H. pylori infection was presented by dominant atrophic changes combined with gastroduodenal reflux (77.6%, p < 0.05) compared to patients without H. pylori infection. Conclusion. Detection of HP infection was peaked in children with CGDP coupled to peptic ulcer disease compared to patients with inflammatory diseases (p < 0.05). Endoscopic examination in HP-positive patients showed that atrophic changes were found by 4-fold more frequently together with gastroduodenal reflux compared to patients without HP infection (p < 0.05).
format	article
author	Sh. T. Turdieva E. A. Shamansurova
author_facet	Sh. T. Turdieva E. A. Shamansurova
author_sort	Sh. T. Turdieva
title	Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori
title_short	Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori
title_full	Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori
title_fullStr	Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori
title_full_unstemmed	Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori
title_sort	features of the endoscopic picture in paediatric gastroduodenal diseases caused by helicobacter pylori
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2020
url	https://doaj.org/article/ddce371e11b64104b034b7541773b905
work_keys_str_mv	AT shtturdieva featuresoftheendoscopicpictureinpaediatricgastroduodenaldiseasescausedbyhelicobacterpylori AT eashamansurova featuresoftheendoscopicpictureinpaediatricgastroduodenaldiseasescausedbyhelicobacterpylori
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Features of the endoscopic picture in paediatric gastroduodenal diseases caused by Helicobacter pylori

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