Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histo...
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Shiraz University of Medical Sciences
2014
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oai:doaj.org-article:ddd51947c37b426a8566baa6013b3cf82021-11-14T07:57:19ZCongenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman2783-243010.17795/acr-17847https://doaj.org/article/ddd51947c37b426a8566baa6013b3cf82014-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_45462_5bdbbc672c4147ac29dd65e6c3bbc96a.pdfhttps://doaj.org/toc/2783-2430Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in colonic anastomosis in dogs. Materials and Methods Eight cross-breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left colon was resected, and end-to-end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the kolmogorov-simirnov test (P = 0.03). Results Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P = 0.01). Conclusions HAM plays a positive role in healing of colonic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs.Saeed DerakhshaniMehran BabaeiMojgan ForootanNakisa MaghsoodiSeyed Ali MajdzadehShiraz University of Medical Sciencesarticlecongenital arteriovenous malformationscolonoscopyrectal bleedingcolitisulcerativeMedicineRENIranian Journal of Colorectal Research, Vol 2, Iss 2, Pp 0-0 (2014) |
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congenital arteriovenous malformations colonoscopy rectal bleeding colitis ulcerative Medicine R |
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congenital arteriovenous malformations colonoscopy rectal bleeding colitis ulcerative Medicine R Saeed Derakhshani Mehran Babaei Mojgan Forootan Nakisa Maghsoodi Seyed Ali Majdzadeh Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman |
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Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in colonic anastomosis in dogs. Materials and Methods Eight cross-breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left colon was resected, and end-to-end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the kolmogorov-simirnov test (P = 0.03). Results Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P = 0.01). Conclusions HAM plays a positive role in healing of colonic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs. |
format |
article |
author |
Saeed Derakhshani Mehran Babaei Mojgan Forootan Nakisa Maghsoodi Seyed Ali Majdzadeh |
author_facet |
Saeed Derakhshani Mehran Babaei Mojgan Forootan Nakisa Maghsoodi Seyed Ali Majdzadeh |
author_sort |
Saeed Derakhshani |
title |
Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman |
title_short |
Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman |
title_full |
Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman |
title_fullStr |
Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman |
title_full_unstemmed |
Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman |
title_sort |
congenital colon arteriovenous malformation misdiagnose in a 25-year-old woman |
publisher |
Shiraz University of Medical Sciences |
publishDate |
2014 |
url |
https://doaj.org/article/ddd51947c37b426a8566baa6013b3cf8 |
work_keys_str_mv |
AT saeedderakhshani congenitalcolonarteriovenousmalformationmisdiagnoseina25yearoldwoman AT mehranbabaei congenitalcolonarteriovenousmalformationmisdiagnoseina25yearoldwoman AT mojganforootan congenitalcolonarteriovenousmalformationmisdiagnoseina25yearoldwoman AT nakisamaghsoodi congenitalcolonarteriovenousmalformationmisdiagnoseina25yearoldwoman AT seyedalimajdzadeh congenitalcolonarteriovenousmalformationmisdiagnoseina25yearoldwoman |
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