Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman

Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histo...

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Autores principales: Saeed Derakhshani, Mehran Babaei, Mojgan Forootan, Nakisa Maghsoodi, Seyed Ali Majdzadeh
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Lenguaje:EN
Publicado: Shiraz University of Medical Sciences 2014
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Acceso en línea:https://doaj.org/article/ddd51947c37b426a8566baa6013b3cf8
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spelling oai:doaj.org-article:ddd51947c37b426a8566baa6013b3cf82021-11-14T07:57:19ZCongenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman2783-243010.17795/acr-17847https://doaj.org/article/ddd51947c37b426a8566baa6013b3cf82014-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_45462_5bdbbc672c4147ac29dd65e6c3bbc96a.pdfhttps://doaj.org/toc/2783-2430Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in colonic anastomosis in dogs. Materials and Methods Eight cross-breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left colon was resected, and end-to-end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the kolmogorov-simirnov test (P = 0.03). Results Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P = 0.01). Conclusions HAM plays a positive role in healing of colonic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs.Saeed DerakhshaniMehran BabaeiMojgan ForootanNakisa MaghsoodiSeyed Ali MajdzadehShiraz University of Medical Sciencesarticlecongenital arteriovenous malformationscolonoscopyrectal bleedingcolitisulcerativeMedicineRENIranian Journal of Colorectal Research, Vol 2, Iss 2, Pp 0-0 (2014)
institution DOAJ
collection DOAJ
language EN
topic congenital arteriovenous malformations
colonoscopy
rectal bleeding
colitis
ulcerative
Medicine
R
spellingShingle congenital arteriovenous malformations
colonoscopy
rectal bleeding
colitis
ulcerative
Medicine
R
Saeed Derakhshani
Mehran Babaei
Mojgan Forootan
Nakisa Maghsoodi
Seyed Ali Majdzadeh
Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
description Background Anastomotic leakage is claimed to be responsible for about one third of deaths following colon surgeries. Therefore, research on applied materials that may prevent leakage and improve healing requires more attention. Objectives This study was conducted to determine surgical and histological outcomes of applying human amniotic membrane (HAM) in colonic anastomosis in dogs. Materials and Methods Eight cross-breed male dogs were divided into two equal groups. After anesthesia and exploration, 5cm of left colon was resected, and end-to-end anastomosis was performed in a single layer. In the treatment group (B), HAM patch measuring 2×3 cm was wrapped around the anastomotic line. Mann-Whitney U test was used to compare the results in the two groups due to small sample size, and normal distribution of data was examined using the kolmogorov-simirnov test (P = 0.03). Results Modified scoring system for surgical wound healing was used to identify the grade of healing in all samples. The healing score was significantly higher in the HAM group (P = 0.01). Conclusions HAM plays a positive role in healing of colonic anastomosis, and would lead to better histological outcomes compared to simple anastomosis in dogs.
format article
author Saeed Derakhshani
Mehran Babaei
Mojgan Forootan
Nakisa Maghsoodi
Seyed Ali Majdzadeh
author_facet Saeed Derakhshani
Mehran Babaei
Mojgan Forootan
Nakisa Maghsoodi
Seyed Ali Majdzadeh
author_sort Saeed Derakhshani
title Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
title_short Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
title_full Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
title_fullStr Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
title_full_unstemmed Congenital Colon Arteriovenous Malformation Misdiagnose in a 25-Year-Old Woman
title_sort congenital colon arteriovenous malformation misdiagnose in a 25-year-old woman
publisher Shiraz University of Medical Sciences
publishDate 2014
url https://doaj.org/article/ddd51947c37b426a8566baa6013b3cf8
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AT nakisamaghsoodi congenitalcolonarteriovenousmalformationmisdiagnoseina25yearoldwoman
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