PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile

Simon Ngao Mule et al. introduce the “PhyloQuant” approach to infer evolutionary relationships of organisms, focusing on the genetically diverse Trypanosoma cruzi strains based on protein expression profiles derived from mass spectrometry. The authors show that phylogenies constructed from their Phy...

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Autores principales:	Simon Ngao Mule, André Guilherme Costa-Martins, Livia Rosa-Fernandes, Gilberto Santos de Oliveira, Carla Monadeli F. Rodrigues, Daniel Quina, Graziella E. Rosein, Marta Maria Geraldes Teixeira, Giuseppe Palmisano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/dde00abd6afc4474a308f48f0fe9f7b4
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spelling	oai:doaj.org-article:dde00abd6afc4474a308f48f0fe9f7b42021-12-02T11:37:25ZPhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile10.1038/s42003-021-01762-62399-3642https://doaj.org/article/dde00abd6afc4474a308f48f0fe9f7b42021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01762-6https://doaj.org/toc/2399-3642Simon Ngao Mule et al. introduce the “PhyloQuant” approach to infer evolutionary relationships of organisms, focusing on the genetically diverse Trypanosoma cruzi strains based on protein expression profiles derived from mass spectrometry. The authors show that phylogenies constructed from their PhyloQuant method and traditional molecular phylogenies are significantly correlated, and demonstrate species-specific proteins and their differential expression over evolutionary time.Simon Ngao MuleAndré Guilherme Costa-MartinsLivia Rosa-FernandesGilberto Santos de OliveiraCarla Monadeli F. RodriguesDaniel QuinaGraziella E. RoseinMarta Maria Geraldes TeixeiraGiuseppe PalmisanoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Simon Ngao Mule André Guilherme Costa-Martins Livia Rosa-Fernandes Gilberto Santos de Oliveira Carla Monadeli F. Rodrigues Daniel Quina Graziella E. Rosein Marta Maria Geraldes Teixeira Giuseppe Palmisano PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
description	Simon Ngao Mule et al. introduce the “PhyloQuant” approach to infer evolutionary relationships of organisms, focusing on the genetically diverse Trypanosoma cruzi strains based on protein expression profiles derived from mass spectrometry. The authors show that phylogenies constructed from their PhyloQuant method and traditional molecular phylogenies are significantly correlated, and demonstrate species-specific proteins and their differential expression over evolutionary time.
format	article
author	Simon Ngao Mule André Guilherme Costa-Martins Livia Rosa-Fernandes Gilberto Santos de Oliveira Carla Monadeli F. Rodrigues Daniel Quina Graziella E. Rosein Marta Maria Geraldes Teixeira Giuseppe Palmisano
author_facet	Simon Ngao Mule André Guilherme Costa-Martins Livia Rosa-Fernandes Gilberto Santos de Oliveira Carla Monadeli F. Rodrigues Daniel Quina Graziella E. Rosein Marta Maria Geraldes Teixeira Giuseppe Palmisano
author_sort	Simon Ngao Mule
title	PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
title_short	PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
title_full	PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
title_fullStr	PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
title_full_unstemmed	PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
title_sort	phyloquant approach provides insights into trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/dde00abd6afc4474a308f48f0fe9f7b4
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PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile

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