Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
Glutaredoxins play a central role in numerous biological processes including cellular redox homeostasis and Fe-S cluster biogenesis. Here the authors establish the molecular basis for glutaredoxin redox catalysis through comprehensive biochemical and structural analyses.
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Nature Portfolio
2020
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oai:doaj.org-article:dde5ff42752f4627a0ede300208a59c02021-12-02T14:40:54ZQuantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins10.1038/s41467-020-15441-32041-1723https://doaj.org/article/dde5ff42752f4627a0ede300208a59c02020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15441-3https://doaj.org/toc/2041-1723Glutaredoxins play a central role in numerous biological processes including cellular redox homeostasis and Fe-S cluster biogenesis. Here the authors establish the molecular basis for glutaredoxin redox catalysis through comprehensive biochemical and structural analyses.Linda LiedgensJannik ZimmermannLucas WäschenbachFabian GeisselHugo LaporteHolger GohlkeBruce MorganMarcel DeponteNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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Science Q |
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Science Q Linda Liedgens Jannik Zimmermann Lucas Wäschenbach Fabian Geissel Hugo Laporte Holger Gohlke Bruce Morgan Marcel Deponte Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
description |
Glutaredoxins play a central role in numerous biological processes including cellular redox homeostasis and Fe-S cluster biogenesis. Here the authors establish the molecular basis for glutaredoxin redox catalysis through comprehensive biochemical and structural analyses. |
format |
article |
author |
Linda Liedgens Jannik Zimmermann Lucas Wäschenbach Fabian Geissel Hugo Laporte Holger Gohlke Bruce Morgan Marcel Deponte |
author_facet |
Linda Liedgens Jannik Zimmermann Lucas Wäschenbach Fabian Geissel Hugo Laporte Holger Gohlke Bruce Morgan Marcel Deponte |
author_sort |
Linda Liedgens |
title |
Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
title_short |
Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
title_full |
Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
title_fullStr |
Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
title_full_unstemmed |
Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
title_sort |
quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/dde5ff42752f4627a0ede300208a59c0 |
work_keys_str_mv |
AT lindaliedgens quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT jannikzimmermann quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT lucaswaschenbach quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT fabiangeissel quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT hugolaporte quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT holgergohlke quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT brucemorgan quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins AT marceldeponte quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins |
_version_ |
1718390140853813248 |