Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins

Glutaredoxins play a central role in numerous biological processes including cellular redox homeostasis and Fe-S cluster biogenesis. Here the authors establish the molecular basis for glutaredoxin redox catalysis through comprehensive biochemical and structural analyses.

Guardado en:
Detalles Bibliográficos
Autores principales: Linda Liedgens, Jannik Zimmermann, Lucas Wäschenbach, Fabian Geissel, Hugo Laporte, Holger Gohlke, Bruce Morgan, Marcel Deponte
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/dde5ff42752f4627a0ede300208a59c0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:dde5ff42752f4627a0ede300208a59c0
record_format dspace
spelling oai:doaj.org-article:dde5ff42752f4627a0ede300208a59c02021-12-02T14:40:54ZQuantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins10.1038/s41467-020-15441-32041-1723https://doaj.org/article/dde5ff42752f4627a0ede300208a59c02020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15441-3https://doaj.org/toc/2041-1723Glutaredoxins play a central role in numerous biological processes including cellular redox homeostasis and Fe-S cluster biogenesis. Here the authors establish the molecular basis for glutaredoxin redox catalysis through comprehensive biochemical and structural analyses.Linda LiedgensJannik ZimmermannLucas WäschenbachFabian GeisselHugo LaporteHolger GohlkeBruce MorganMarcel DeponteNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Linda Liedgens
Jannik Zimmermann
Lucas Wäschenbach
Fabian Geissel
Hugo Laporte
Holger Gohlke
Bruce Morgan
Marcel Deponte
Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
description Glutaredoxins play a central role in numerous biological processes including cellular redox homeostasis and Fe-S cluster biogenesis. Here the authors establish the molecular basis for glutaredoxin redox catalysis through comprehensive biochemical and structural analyses.
format article
author Linda Liedgens
Jannik Zimmermann
Lucas Wäschenbach
Fabian Geissel
Hugo Laporte
Holger Gohlke
Bruce Morgan
Marcel Deponte
author_facet Linda Liedgens
Jannik Zimmermann
Lucas Wäschenbach
Fabian Geissel
Hugo Laporte
Holger Gohlke
Bruce Morgan
Marcel Deponte
author_sort Linda Liedgens
title Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
title_short Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
title_full Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
title_fullStr Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
title_full_unstemmed Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
title_sort quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/dde5ff42752f4627a0ede300208a59c0
work_keys_str_mv AT lindaliedgens quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT jannikzimmermann quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT lucaswaschenbach quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT fabiangeissel quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT hugolaporte quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT holgergohlke quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT brucemorgan quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
AT marceldeponte quantitativeassessmentofthedeterminantstructuraldifferencesbetweenredoxactiveandinactiveglutaredoxins
_version_ 1718390140853813248