Integrative modeling of membrane-associated protein assemblies

Most approaches for modeling the membrane protein complexes are not capable of incorporating the topological information provided by the membrane. Here authors present an integrative computational protocol for the modeling of membrane-associated protein assemblies, specifically complexes consisting...

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Autores principales: Jorge Roel-Touris, Brian Jiménez-García, Alexandre M. J. J. Bonvin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ddecf94631954d58846ce015c43e0b7e
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spelling oai:doaj.org-article:ddecf94631954d58846ce015c43e0b7e2021-12-02T14:41:23ZIntegrative modeling of membrane-associated protein assemblies10.1038/s41467-020-20076-52041-1723https://doaj.org/article/ddecf94631954d58846ce015c43e0b7e2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20076-5https://doaj.org/toc/2041-1723Most approaches for modeling the membrane protein complexes are not capable of incorporating the topological information provided by the membrane. Here authors present an integrative computational protocol for the modeling of membrane-associated protein assemblies, specifically complexes consisting of a membrane-embedded protein and a soluble partner.Jorge Roel-TourisBrian Jiménez-GarcíaAlexandre M. J. J. BonvinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jorge Roel-Touris
Brian Jiménez-García
Alexandre M. J. J. Bonvin
Integrative modeling of membrane-associated protein assemblies
description Most approaches for modeling the membrane protein complexes are not capable of incorporating the topological information provided by the membrane. Here authors present an integrative computational protocol for the modeling of membrane-associated protein assemblies, specifically complexes consisting of a membrane-embedded protein and a soluble partner.
format article
author Jorge Roel-Touris
Brian Jiménez-García
Alexandre M. J. J. Bonvin
author_facet Jorge Roel-Touris
Brian Jiménez-García
Alexandre M. J. J. Bonvin
author_sort Jorge Roel-Touris
title Integrative modeling of membrane-associated protein assemblies
title_short Integrative modeling of membrane-associated protein assemblies
title_full Integrative modeling of membrane-associated protein assemblies
title_fullStr Integrative modeling of membrane-associated protein assemblies
title_full_unstemmed Integrative modeling of membrane-associated protein assemblies
title_sort integrative modeling of membrane-associated protein assemblies
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ddecf94631954d58846ce015c43e0b7e
work_keys_str_mv AT jorgeroeltouris integrativemodelingofmembraneassociatedproteinassemblies
AT brianjimenezgarcia integrativemodelingofmembraneassociatedproteinassemblies
AT alexandremjjbonvin integrativemodelingofmembraneassociatedproteinassemblies
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