Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ
Professional antigen presenting cells (APC) are the major activator of T cells that then hone to sites of inflammation. Using islet cell grafts, here the authors show that parenchymal cells can present antigen to activate CD8+T cells at inflammatory sites, coining this a ‘mezzanine response’ distinc...
Guardado en:
Autores principales: | Robyn M. Sutherland, Sarah L. Londrigan, Jamie L. Brady, Emma M. Carrington, Julia M. Marchingo, Susanne Heinzel, Philip D. Hodgkin, Kate L. Graham, Thomas W. Kay, Yifan Zhan, Andrew M. Lew |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ddf258470896415aaf2e07fd3e6bba40 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
T-cell stimuli independently sum to regulate an inherited clonal division fate
por: J. M. Marchingo, et al.
Publicado: (2016) -
Target-dependent biogenesis of cognate microRNAs in human cells
por: Mainak Bose, et al.
Publicado: (2016) - Deuterocanonical and cognate literature yearbook
-
Single-cell RNA transcriptome landscape of hepatocytes and non-parenchymal cells in healthy and NAFLD mouse liver
por: Qi Su, et al.
Publicado: (2021) -
Type-3 Hyaluronan Synthase Attenuates Tumor Cells Invasion in Human Mammary Parenchymal Tissues
por: Wen-Jui Lee, et al.
Publicado: (2021)