Induction of a local muscular dystrophy using electroporation in vivo: an easy tool for screening therapeutics

Abstract Intramuscular injection and electroporation of naked plasmid DNA (IMEP) has emerged as a potential alternative to viral vector injection for transgene expression into skeletal muscles. In this study, IMEP was used to express the DUX4 gene into mouse tibialis anterior muscle. DUX4 is normall...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Aline Derenne, Alexandra Tassin, Thuy Hang Nguyen, Estelle De Roeck, Vincianne Jenart, Eugénie Ansseau, Alexandra Belayew, Frédérique Coppée, Anne-Emilie Declèves, Alexandre Legrand
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
R
Q
Acceso en línea:https://doaj.org/article/de019a5459f549d595a0412b6acbd90b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares