Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens

Abstract Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment...

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Autores principales:	Waheeb Sakran, Zufit Hexner-Erlichman, Ronen Spiegel, Hamed Batheesh, Raphael Halevy, Ariel Koren
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/de0204269cfc4168aeb31fac7797e528
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spelling	oai:doaj.org-article:de0204269cfc4168aeb31fac7797e5282021-12-02T18:17:42ZCampylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens10.1038/s41598-020-62744-y2045-2322https://doaj.org/article/de0204269cfc4168aeb31fac7797e5282020-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-62744-yhttps://doaj.org/toc/2045-2322Abstract Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment. In cases of protracted diarrhoea in healthy children or immunocompromised patients, antibiotic treatment is recommended, and the drug of choice is still macrolides, with very low resistance rates in Campylobacter species. However, it is crucial to isolate the causative organism, because some cases, such as Shigella encephalitis, call for initiation of empiric antibiotic treatment. In this study, we compared the incidence, epidemiology, clinical findings and laboratory results of gastroenteritis with dysentery caused by these organisms in children in our area. C. jejuni was found to be the leading pathogen in children hospitalized with bacterial gastroenteritis, followed by Shigella and Salmonella. Macrolides were the drug of choice for Campylobacter, and ceftriaxone and ciprofloxacin were the best empiric treatments for Shigella and Salmonella, respectively.Waheeb SakranZufit Hexner-ErlichmanRonen SpiegelHamed BatheeshRaphael HalevyAriel KorenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-5 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Waheeb Sakran Zufit Hexner-Erlichman Ronen Spiegel Hamed Batheesh Raphael Halevy Ariel Koren Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens
description	Abstract Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment. In cases of protracted diarrhoea in healthy children or immunocompromised patients, antibiotic treatment is recommended, and the drug of choice is still macrolides, with very low resistance rates in Campylobacter species. However, it is crucial to isolate the causative organism, because some cases, such as Shigella encephalitis, call for initiation of empiric antibiotic treatment. In this study, we compared the incidence, epidemiology, clinical findings and laboratory results of gastroenteritis with dysentery caused by these organisms in children in our area. C. jejuni was found to be the leading pathogen in children hospitalized with bacterial gastroenteritis, followed by Shigella and Salmonella. Macrolides were the drug of choice for Campylobacter, and ceftriaxone and ciprofloxacin were the best empiric treatments for Shigella and Salmonella, respectively.
format	article
author	Waheeb Sakran Zufit Hexner-Erlichman Ronen Spiegel Hamed Batheesh Raphael Halevy Ariel Koren
author_facet	Waheeb Sakran Zufit Hexner-Erlichman Ronen Spiegel Hamed Batheesh Raphael Halevy Ariel Koren
author_sort	Waheeb Sakran
title	Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens
title_short	Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens
title_full	Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens
title_fullStr	Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens
title_full_unstemmed	Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens
title_sort	campylobacter gastroenteritis in children in north-eastern israel comparison with other common pathogens
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/de0204269cfc4168aeb31fac7797e528
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Campylobacter gastroenteritis in children in north-eastern Israel comparison with other common pathogens

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