Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis

Abstract Endosomal trafficking of cell surface receptors is essential to their function. Integrins are transmembrane receptors that integrate adhesion to the extracellular matrix with engagement of the cytoskeleton. Ligated integrins mediate diverse signals that regulate matrix assembly, cell surviv...

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Autores principales: Maisel J. Caliva, Won Seok Yang, Shirley Young-Robbins, Ming Zhou, Hana Yoon, Michelle L. Matter, Mark L. Grimes, Thomas Conrads, Joe William Ramos
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/de03163bffee45e4a081229dd13ce7cd
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