Loss of GCNT2/I-branched glycans enhances melanoma growth and survival

Aberrant glycosylation patterns on cancer cells promote several pro-tumorigenic functions, including enhancing tumor cell proliferation. Here the authors provide data that show melanoma cells downregulate GCNT2 with consequent loss of I-branched glycans; this leads to the formation of extended i-lin...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jenna Geddes Sweeney, Jennifer Liang, Aristotelis Antonopoulos, Nicholas Giovannone, Shuli Kang, Tony S. Mondala, Steven R. Head, Sandra L. King, Yoshihiko Tani, Danielle Brackett, Anne Dell, George F. Murphy, Stuart M. Haslam, Hans R. Widlund, Charles J. Dimitroff
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/de097a28a8eb4a7595203ca85b7c7bc9
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!