Bystander Host Cell Killing Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin

Bystander Host Cell Killing Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin

ABSTRACT Clostridium perfringens enterotoxin (CPE) binds to claudin receptors, e.g., claudin-4, and then forms a pore that triggers cell death. Pure cultures of host cells that do not express claudin receptors, e.g., fibroblasts, are unaffected by pathophysiologically relevant CPE concentrations in...

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Autores principales: Archana Shrestha, Matthew R. Hendricks, Jennifer M. Bomberger, Bruce A. McClane
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/de0a0e4ae92f4adba6bf1dd16c8066e2
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